Pilot Study of Myocardial Effects Following an Endurance Race

Last updated: April 23, 2019
Sponsor: University Hospital, Linkoeping
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT03549364
2017/429-31
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Ten healthy subjects perform a baseline computer tomography (CT) of the heart and routine laboratory blood tests for myocardial injury and inflammation.

The same data are collected <24 hours after an endurance race corresponding to a maraton run (i.e. about 40 km of running and/or about 2.5 hours hard training or more). A third collection of lab tests and CT is done a couple of weeks after the race. Magnetic resonance imaging is also performed in parallell to the CT on occasions 2 and 3 in most subjects, serving as a reference for determination of myocardial blood flow.

Eligibility Criteria

Inclusion

Inclusion Criteria: Healthy subjects, experienced in long distance running

Exclusion

Exclusion Criteria: Significant renal, kidney, heart, liver or musculoskeletal disease.

Study Design

Total Participants: 10
Study Start date:
May 24, 2018
Estimated Completion Date:
December 31, 2019

Study Description

Ten healthy subjects perform a baseline computer tomography (CT) of the heart and routine laboratory blood tests (troponin T, hs-CRP, CK-mb etc) for myocardial injury and inflammation.

The same data are collected <24 hours after an endurance race corresponding to a maraton run (i.e. about 40 km of running and/or about 2.5 hours hard training or more). A third collection of lab tests and CT is done a couple of weeks after the race. Magnetic resonance imaging (MRI) is also performed in parallell to the CT on occasions 2 and 3 in most subjects, serving as a reference for determination of myocardial blood flow. The CT of the heart includes contrast injection and blood flow will be determined by a recently developed based on very powerful computers using "machine learning".

Connect with a study center

  • University Hospital of Linkoping

    Linkoping, 58185
    Sweden

    Active - Recruiting

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