Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor

Last updated: July 31, 2018
Sponsor: Recep Tayyip Erdogan University Training and Research Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pregnancy

Miscarriage

Pregnancy Complications

Treatment

N/A

Clinical Study ID

NCT03610841
40465587-26
  • Ages 21-34
  • Female

Study Summary

The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preterm labor.

The secondary objective of the study is to analyze the relationship between preterm labor and periodontal infection, using clinical, biochemical and microbiological methods.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • pregnant women with preterm labor

    1. weeks of pregnant women with no history of preterm labor

Exclusion

Exclusion Criteria:

  • Genitourinary infection

  • pregnancy or pre-pregnancy hypertension

  • HIV infection

  • diabetes mellitus

  • multiple pregnancy, preterm labor / low birth weight

  • smoker and alcohol use history

  • IVF pregnancy

  • placental, cervical and uterine anomalies

  • pregnancy with intrauterine growth retardation

  • pregnancies with congenital or chromosomal fetal anomalies

  • significant vaginal bleeding

  • infertility stories

  • drug addicts

  • poor socioeconomic level

Study Design

Total Participants: 100
Study Start date:
February 17, 2018
Estimated Completion Date:
December 15, 2018

Study Description

Preterm infants are born prior to completion of 37 weeks of gestation. Periodontal disease is a subclinical and persistent infection source which induces the systemic inflammatory reactions and increases the risk of preterm labor. It is believed that the results will set light to the etiology of preterm labor and will help to develop strategies to prevent the disease.

Connect with a study center

  • Recep Tayyip Erdogan University

    Rize, 53000
    Turkey

    Site Not Available

  • Recep Tayyip Erdogan University Dentistry Faculty

    Rize, 53000
    Turkey

    Site Not Available

  • Recep Tayyip Erdogan University Faculty of Medicine

    Rize, 53000
    Turkey

    Site Not Available

  • Ege University Dentistry Faculty

    İzmir,
    Turkey

    Active - Recruiting

  • İzmir Health Sciences University, Tepecik Training and Research Hospital Department of Obstetrics and Gynecology

    İzmir,
    Turkey

    Active - Recruiting

  • Glaskow Dental School , School of Medicine University of Glasgow

    Glaskow,
    United Kingdom

    Site Not Available

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