Optimization Strategy of Carotid Artery Stenosis

Last updated: November 28, 2022
Sponsor: Peking Union Medical College Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carotid Artery Disease

Treatment

N/A

Clinical Study ID

NCT05629000
PUMCH-CAS-006
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The goal of this observational study is to learn about how to utilize multiple evaluation techniques in carotid artery stenosis patients for optimizing assessment of diagnosis and treatment strategy.

The main questions it aims to answer are:

  • Identify best strategy that use multi-modal MRI and CT to assess patients' cerebral lesions and perfusion.

  • Identify best strategy that use multi-modal MRI, PET-MRI ultrasound and CT to assess components and characters of patients' carotid plaques.

Participants will accept imaging examination before and after surgery. And doctors will collect basic characteristics, imaging results and biological samples of patients for analysis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. patients with severe stenosis (≥50%) or near-occlusion diagnosed by computedtomographic angiogram;
  2. patients received carotid endarterectomy at Peking Union Medical College Hospital

Exclusion

Exclusion Criteria:

(1) Any contraindication to image examination; (3) refuse to sign the Informed consent.

Study Design

Total Participants: 1000
Study Start date:
January 01, 2015
Estimated Completion Date:
December 31, 2026

Connect with a study center

  • vascular surgery department of PUMCH

    Beijing, Beijing 100730
    China

    Active - Recruiting

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