Chorioretinal Vascularization and Electrophysiological Changes After Carotid Revascularization

Last updated: July 3, 2023
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carotid Artery Disease

Treatment

Optical coherence tomography angiography and pattern electroretinogram

Clinical Study ID

NCT05835869
5532
  • Ages > 18
  • All Genders

Study Summary

The aim of the study is to evaluate changes in retinal function by means of electro-functional examinations of the retina and to associate them with any changes in chorioretinal vascular density occurring in the ipsilateral eye after carotid revascularization surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • age >18 years old
  • Carotid stenosis diagnosis with indication to perform carotid endarterectomy
  • informed consent form signing

Exclusion

Exclusion Criteria:

  • age <18 years old
  • recurrent intraocular inflammation
  • retinal disease
  • optic neuropathy, optic nerve drusen, opacity of the dioptric means in the pre- orpost-operative period that prevents the acquisition of high-resolution images
  • unstable fixation
  • spheric refractive error > +/- 6 D spheric and/or +/- 3 D cylinder
  • history of prior ocular surgery
  • refusal of signing informed consent form

Study Design

Total Participants: 30
Treatment Group(s): 1
Primary Treatment: Optical coherence tomography angiography and pattern electroretinogram
Phase:
Study Start date:
April 20, 2023
Estimated Completion Date:
April 30, 2024

Connect with a study center

  • Policlinico Agostino Gemelli IRCCS

    Roma, RM 00168
    Italy

    Active - Recruiting

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