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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (84) clinical trials

Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.

Patient with severe asthma attack, will be admitted to observation area in PEC and assessed for eligibility to the study by attending physician based on our study inclusion criteria. Eligible patient will be enrolled after obtaining written consent. Patient will receive routine treatment for severe asthma attack like,inhaled bronchodilators plus ...

Phase

Effect of OC000459 on Eosinophilic Airway Inflammation in Severe Asthma

At week 12 subjects not on oral corticosteroids (OCS) will complete the treatment period and return after 4 weeks for final follow up visit. Those subjects who were taking OCS at baseline will continue for a maximum of 12 additional weeks, double blind period during which their current OCS treatment ...

Phase

Growth of Airways and Lung Tissues in Premature and Healthy Infants

SPECIFIC AIM # 1: Determine the relationship between parenchymal tissue and alveolar volume with normal lung growth early in life We hypothesize that during the first two years of life that parenchymal surface area and alveolar volume increase with somatic growth; however, the ratio of surface area to volume remains ...

Phase N/A

Assessment of Lung Structure and Function of Infants Born Prematurely

SPECIFIC AIM #1: Determine the relationship between parenchymal tissue and alveolar volume with normal lung growth early in life. We hypothesize that during the first two years of life that parenchymal surface area and alveolar volume increase with somatic growth; however, the ratio of surface area to volume remains constant, ...

Phase N/A

MRI as a Means to Measure Lung Function: Non-Invasive Imaging in Neonates and Children

The purpose of this study is to develop rapid MRI techniques for imaging the lung with hyperpolarized helium-3 gas as an inhaled contrast agent. These techniques will be piloted in adults and older children before testing them in younger children and infants. The purpose is to enable imaging of non-sedated ...

Phase N/A

Analysis of Inflammation and Microbiome in Patients With Sinusitis and Asthma

This is a cross-sectional and non-interventional study to investigate mechanisms of disease in patients with asthma who have concomitant chronic sinusitis and/or nasal polyps (upper airway disease). Approximately 160 participants will be enrolled. Patients who are scheduled to undergo inpatient or outpatient endoscopic sinus surgery at the University of California ...

Phase N/A

Obstructive Airways Diseases in Pulmonary Clinic (OADPC) Study

This is an observational study which aims to evaluate the possibility of using data from a capnography device to assess obstructive airway severity in both COPD and Asthma patients. The study will include adult asthma and COPD patients (age >18). Patients will be enrolled on a continuous basis and will ...

Phase N/A

Laminar Airflow in Severe Asthma for Exacerbation Reduction - 48 Month Follow-up.

Asthma affects over 5.4 million people in the UK with nearly 500,00 experiencing severe symptoms and frequent exacerbations that are inadequately controlled with available treatments. The burden of severe asthma on the NHS is enormous accounting for 80% of total asthma cost. In 2009 there were 1131 deaths due to ...

Phase N/A

A Pragmatic Trial of Corticosteroid Optimisation in Severe Asthma

Asthma affects an estimated 300 million people worldwide with a population prevalence of ca 15% in the UK. The WHO has estimated UK disability adjusted life-years per 100,000 population for asthma to be greater than diabetes and breast cancer. Much of this excessive disability is in the 10-20% of patients ...

Phase N/A

Study to Assess the Efficacy and Safety of Omalizumab Treatment on ICS Reduction for Severe IgE-mediated Asthma

This is a multicentric, open label, randomized, parallel-group study with a 12-month treatment period. Patients will be assigned to one of the 2 treatment groups, omalizumab plus budesonide/formoterol or budesonide/formoterol alone. The study comprises 4 phases: During the 4-week run-in phase adult patients will receive budesonide 800 mg and formoterol ...

Phase