Profile
Contact Information
Center Information
Betty-Jane Sloan, MA, CCRCClinical Research Manager
The Rogosin Institute
504 E. 74th St., 5th Floor
New York, NY 10021
646.317.0701
212.249.4659
bjsloan@nyp.org
www.rogosin.org
Currently Enrolling Trials
- CASCADE FH Registry: Cascade Screening for Awareness and Detection of Familial Hypercholesterolemia
- RENAL AID: Repository of Novel Analytes Leading to Autoimmune, Inflammatory, and Diabetic Nephropathies
Overview
The Rogosin Institute was established in 1983 as an independent, not-for-profit institution for research and health care specializing in kidney disease including chronic kidney failure, diabetic kidney disease, polycystic kidney disease, end stage renal disease and transplantation, and cardiovascular disease due to cholesterol and other lipid disorders, hypertension, diabetes, cancer and sepsis.
The Rogosin Institute is affiliated with New York-Presbyterian Hospital/Weill Cornell Medicine and is a corporate member of New York-Presbyterian Regional Hospital Network. Rogosin Institute members are on the staff of New York-Presbyterian Hospital and have appointments at Weill Cornell Medical College. Several are also on the adjunct faculty at The Rockefeller University.
Research Experience
The Rogosin Institute has been involved in clinical research since its inception in 1983. Phase 1 to 4 studies and investigator-initiated studies are conducted. Our therapeutic interests and clinical trial experience with more than 50 pharmaceutical companies and contract research organizations include:
- End-stage renal disease (ESRD) involving subjects who are on hemodialysis, peritoneal dialysis or home nocturnal hemodialysis
- Polycystic kidney disease
- Chronic kidney disease (CKD) involving subjects who are predialysis
- Diabetic kidney disease
- Hypertension; primary and secondary to kidney disease
- Kidney and kidney/pancreas transplantations
- Behavioral health
- Cardiovascular disease
- Dyslipidemia disorders
- Hypercholesterolemia
- Familial hypercholesterolemia, including adult and pediatric homozygous and heterozygous familial hypercholesterolemia (HoFH and HeFH)
- Diabetes
- Cancer
- Sepsis
Facility Description
The Rogosin Institute has clinical facilities in Manhattan at New York Presbyterian Hospital/Weill Cornell Medical College as well as in Queens and Brooklyn. The Rogosin Institute offers both outpatient facilities and inpatient facilities. Research facilities are also located in Xenia, Ohio.
Rogosin Institute outpatient facilities include:
- Jack J. Dreyfus Clinic, an outpatient facility for the prevention and treatment of kidney disease;
- Susan R. Knafel Polycystic Disease Center, located within the Jack J. Dreyfus Clinic, to diagnose, prevent and treat complications related to polycystic kidney disease;
- Hemodialysis centers located in Manhattan, Queens and Brooklyn;
- David D. Thompson Transplantation Center for kidney transplants and simultaneous pancreas-kidney transplants; and
- Maurice R. Greenberg Comprehensive Lipid Control Center for prevention and treatment of atherosclerosis and its risk factors for adults and children.
Rogosin Institute inpatient facilities in New York-Presbyterian Hospital/Weill Cornell Medical College include:
- The Rogosin Institute Wing for patients requiring hospitalization for kidney disease- related problems and kidney transplantation; and
- The Rogosin Institute Ralph J. Bunch Dialysis and Apheresis Center for patients undergoing intensive care hemodialysis or LDL-apheresis, which is a specialized treatment for severe genetic hypercholesterolemia.
Investigator Experience
The investigators at The Rogosin Institute include 23 physicians and four PhDs. The clinical research program offers a clinical research manager, research nurse practitioners and full-time clinical research coordinators.
Bruce R. Gordon, MD
Cholesterol and lipid disorders, plasmapheresis
Dr. Gordon is the director of the clinical research program, executive vice president, and co-director of The Rogosin Institute’s Maurice R. Greenberg Comprehensive Lipid Control Center. He is a professor of clinical medicine and surgery at Weill Cornell Medical College and an attending physician at New York-Presbyterian Hospital. Dr. Gordon has overall responsibility of the clinical research program and has been conducting clinical research for more than 40 years. His research focuses primarily on lipids and cardiovascular research at the Comprehensive Lipid Control Center.
Betty-Jane Sloan, BS, MA
Certified Clinical Research Coordinator
Ms. Sloan has more than 30 years of experience in clinical research at The Rogosin Institute and is the manager for the clinical research program. Ms. Sloan is a staff associate in the Department of Medicine at Weill Cornell Medical College.
Irina Barash, MD
Polycystic kidney disease
Nephrology
Nathaniel Berman, MD
Nephrology
Jon Blumenfeld, MD
Polycystic kidney disease
Nephrology
Hypertension
Andrew Bohmart, MD
Nephrology
James Chevalier, MD
Nephrology
Daniel Cukor, PhD
Behavioral health
David Epstein, MD
Nephrology
Dalia Frumkin, MD
Nephrology
Gail Frumkin, MD
Nephrology
Choli Hartono, MD
Nephrology/transplantation
Lisa Hudgins, MD
Lipids/pediatric lipids
Chun Lam, MD
Nephrology
Jun Lee, MD
Nephrology/transplantation
Daniel Levine, PhD
Lipids/biochemistry
Minji Li, MD
Nephrology
Jonathan Lin, MD
Nephrology
Frank Liu, MD
Nephrology
Home hemodialysis
Kotresha Neelakantappa, MD
Nephrology
Leif Oxburgh, PhD
Kidney regenerative medicine
Thomas Parker, PhD
Lipids/biochemistry
Alan Perlman, MD
Nephrology
Diabetic nephropathy
Stuart Saal, MD
Nephrology
Transplantation
Lipids
Jeffrey Silberzweig, MD
Nephrology
Vesh Srivatana, MD
Nephrology
Peritoneal dialysis
Laurence Stam, MD
Nephrology
John Wang, MD, PhD
Nephrology
Staff Expertise
The Rogosin Institute employs a highly trained staff of more than 575 professionals, including physicians, nurse practitioners, registered nurses, social workers, dialysis technicians, phlebotomy technicians, basic and clinical research staff, and registered dietitians.
Patient Demographics
The Rogosin Institute’s patient facilities are located in New York City, Brooklyn and Queens and include eight dialysis centers. Patients mainly come from the greater New York and tri-state area, which is populated with approximately 20,000,000 people. The Rogosin Institute has access to many diverse nationalities and ages.
Other Information
Institutional Review Boards: The Rogosin Institute can conduct clinical research studies using either central (commercial) IRBs or the local IRBs of Weill Cornell Medical College or The Rockefeller University.
Clinical and Translational Science Centers: The Rogosin Institute has access to Clinical and Translational Science Centers (CTSC) at both New York-Presbyterian Hospital/Weill Cornell Medical College and The Rockefeller University.
Information Technology: The Rogosin Institute employs a full-time database systems manager to provide our investigators with data management for investigator-initiated studies.
Electronic Medical Records: The Rogosin Institute utilizes Allscripts and Darwin electronic medical record systems. These provide immediate access to information on a patient’s history, treatment and laboratory data at all Rogosin Institute facilities and NewYork-Presbyterian Hospital/Weill Cornell Medical College.
Federal-wide Assurance: The Rogosin Institute holds a Federalwide Assurance (FWA 00005225) registered with the Office for Human Research Protection (OHRP).