Theorem Clinical Research

R&D Trends

Cancer Research U.K. launches $16M biotherapeutics funding scheme

Wednesday, October 22, 2014 11:43 AM

Cancer Research U.K. has launched a new biotherapeutics funding schemes to give new opportunities to scientists and clinicians to harness the power of biotherapeutic treatments. Applications for the award will be judged on the potential of turning the research findings into new preventative, diagnostic or therapeutic approaches for cancer.

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SBRI Healthcare launches $4M competition

Wednesday, October 22, 2014 11:41 AM

Small Business Research Initiative (SBRI) Healthcare, an NHS England funded initiative to develop innovative products that address unmet health needs, has launched the latest SBRI Healthcare competition, which aims to accelerate development and NHS adoption of new technologies. In the second tranche of funding this year, a further $4 million is on offer to companies working in priority healthcare areas, including brain injury; child and adolescent mental health; diabetic foot ulcers; imaging; and outpatient services.

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Inovio Pharmaceuticals, MedImmune, University of Pennsylvania partner

Wednesday, October 22, 2014 11:39 AM

The Defense Advanced Research Projects Agency (DARPA) has awarded $12.2 million for a collaborative study that will be conducted by scientists from the Perelman School of Medicine at the University of PennsylvaniaInovio Pharmaceuticals and MedImmune, the global biologics R&D arm of AstraZeneca. The group will develop DNA-based monoclonal antibodies (mAbs) for infectious disease treatment. DARPA is an agency of the U.S. Department of Defense that creates and supports novel technologies important for national security.

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National Alzheimer's Plan milestones must be strengthened to meet 2025 goal

Wednesday, October 22, 2014 11:33 AM

The U.S. government has initiated a major effort to prevent and effectively treat Alzheimer's disease by 2025. However, a workgroup of nearly 40 Alzheimer's researchers and scientists said the research milestones in the U.S. government's National Plan to Address Alzheimer's Disease must be broadened in scope, increased in scale and adequately funded in order to successfully achieve this goal. A series of proposals by the workgroup to enlarge and strengthen the plan have been published in Alzheimer's & Dementia: the Journal of the Alzheimer's Association.

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Physicians to pharmas: provide patient services or face irrelevance

Friday, October 17, 2014 02:49 PM

Physicians are looking to pharmaceutical companies to help them keep patients engaged in their healthcare by providing patient services, according to the ePharma Physician 2014 study from Manhattan Research, part of Burlington, Mass.-based Decision Resources Group.

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Cardiorentis, Roche collaborate on Ularitide

Friday, October 17, 2014 12:49 PM

Cardiorentis, a Switzerland-based, privately held biopharmaceutical company, is collaborating with Roche to establish the therapeutic efficacy and safety of Ularitide, the company's investigational drug for acute heart failure (AHF). Cardiorentis will incorporate Roche's advanced in vitro diagnostic tests into its TRUE-AHF phase III study to characterize the pharmacological properties of Ularitide, evaluate its benefit-risk profile and the appropriate clinical application in patients.

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Sanofi Pasteur, Immune Design collaborate on herpes simplex virus therapy

Friday, October 17, 2014 12:48 PM

Immune Design, a California-based clinical-stage immunotherapy company, has entered into a broad collaboration for the development of a herpes simplex virus (HSV) immune therapy with Sanofi Pasteur, the vaccines division of Sanofi.

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AstraZeneca, University of Cambridge strengthen partnership

Friday, October 17, 2014 12:46 PM

AstraZeneca, together with its global biologics R&D arm MedImmune, has entered into four new collaborations with the University of Cambridge, building further on their existing partnership. The latest collaborations reinforce AZ’s commitment to creating a permeable research infrastructure in Cambridge following its decision to locate one of its three global R&D centers and its global headquarters in the city, which has been home to MedImmune’s biologics research laboratories for 25 years.

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Aduro, Johnson & Johnson Innovation and Janssen expand collaboration

Friday, October 17, 2014 12:44 PM

Aduro BioTech, a Berkeley, Calif.-based, private, clinical-stage biotechnology company focused on immunotherapy for cancer, has entered into its second agreement with Janssen Biotech, part of Johnson & Johnson, granting an exclusive, worldwide license to certain product candidates engineered for the treatment of lung cancer and certain other cancers based on its novel LADD immunotherapy platform.

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Treeway, LACDR collaborate on ALS therapy development

Thursday, October 16, 2014 02:36 PM

Treeway, a Netherlands-based, amyotrophic lateral sclerosis (ALS) R&D strategy-focused company, and the Leiden Academic Center for Drug Research (LACDR) at the University of Leiden, the Netherlands, have formed a collaboration focused on the optimization of clinical trial designs and data analysis for ALS through the use of population disease progression models. Both parties aim to obtain a better understanding of the disease by developing ALS physiology-based disease models and test the effect of interventions in the different identified pathways.

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