Profile
Center Information
Albert Einstein College of Medicine (East Campus)
1300 Morris Park Ave.
Block Bldg., 5th Floor
Bronx, NY 10461
718.430.2500
ICTR@einsteinmed.org
www.research.montefioreeinstein.org
Currently Enrolling Trials
- NICE-AD (Neurostimulation for Cognitive Enhancement in Alzheimer’s Disease)
- Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial
- Adolescent BV - Impact of the vaginal microbiome on topical HIV pre-exposure prophylaxis (PrEP)
- Autism Genetics Network:Increasing Representation of Human Diversity
- Behavioral Predictors of Illness Progression in Adolescent Depression
- Hospital Airway Resuscitation Trial (HART)
- MACS/WIHS Combined Cohort Study
- Re-assessment of diagnostic cortisol values for adrenal insufficiency using a highly specific cortisol assay
- Visual-somatosensory integration as a novel marker of Alzheimer's Disease
Overview
The Block Institute for Clinical and Translational Research (ICTR) represents a partnership between the Albert Einstein College of Medicine and Montefiore Health System, and has been continuously funded since 2008 by a Clinical and Translational Science Award (CTSA) from the NIH National Center for Advancing Translational Sciences (NCATS). Since the Institute’s founding in 2007, the ICTR has been committed to providing critical research infrastructure to promote efficient translation of scientific discoveries into improved patient outcomes, funding innovative clinical and translational research, advancing use of state-of-the-art technologies to access and analyze data, and engaging patients and community members throughout the research process. The ICTR also has a mission to train clinical and translational researchers, and create a skilled and diverse research workforce. We have developed strong collaborations with our community and government leaders, industry, and other institutions that have led to impactful achievements across the translational research spectrum.
Albert Einstein College of Medicine and the Montefiore Health System
The Albert Einstein College of Medicine is a premier biomedical research institution with ~$200 million of annual grant funding and seven NIH-funded research centers. Montefiore Health System serves over 1.5 million patients across the geographically, socioeconomically, racially, and ethnically diverse areas of the Bronx, Westchester, and lower Hudson Valley. The health system serves approximately 35% of the Bronx population, which disproportionately suffers from high rates of diabetes, obesity, asthma, substance use disorder, HIV/AIDS and other poor health outcomes. At the core of Einstein and Montefiore has always been a commitment to equitable access to health care, education, and research for all people in our communities. More than 70% of Montefiore Health System patients enrolled in clinical studies self-report as Hispanic or Black. We are also one of only 10 US institutions that have a Clinical and Translational Science Award, Intellectual and Developmental Disabilities Research Center, and a University Center of Excellence in Developmental Disabilities.
Of Montefiore Health System’s 11 acute care facilities, four are integrated hospitals in the Bronx known as Montefiore Medical Center. Montefiore Health System is comprised of more than 2,000 providers and spans 11 hospitals, including the Children's Hospital at Montefiore, Burke Rehabilitation Hospital and more than 200 outpatient ambulatory care sites. The health system derives its inspiration for excellence from its patients and community and continues to be on the front lines of developing innovative approaches to care.
Research Experience
Einstein-Montefiore Research and Treatment Milestones
- Montefiore was among the first hospitals to establish departments of social services (1914), home healthcare (1947) and social medicine (1950).
- In 1994, it became the only New York City medical school selected by the NIH to participate in the Women's Health Treatment Initiative, the largest research study of women's health ever.
- The state-of-the-art Children's Hospital at Montefiore (CHAM) opened in 2001 and quickly in 2004 earned a world-class reputation for pediatric care with our successful separation of twins conjoined at the head.
- In 2006, it was the only medical institution in the northeast to serve as a research site for the Hispanic Community Health Study, the largest research study of Hispanic health ever.
- Leader of the Bronx Regional Health Information Organization (Bronx RHIO), a Bronx-wide consortium intended to facilitate clinical information exchange. The purpose is to build a secure, interoperable health information exchange that will promote patient-centered, rational, cost-effective treatments throughout the system.
- Demonstrated the association between reduced levels of high-density lipoproteins (HDL) or "good" cholesterol, and heart disease.
- Helped to develop ground-breaking new protocols for the treatment of diabetes based on more sophisticated methods of monitoring glucose levels.
- Developed pioneering techniques, including three types of regional chemotherapy treatments, for the diagnosis and treatment of cancer based on the genetics of both the tumor and the patient.
- Developed treatments and technology that revolutionized medical care, such as the cardiac pacemaker and cardiac catherization, now used worldwide.
- In 2011, Montefiore was recognized by the Centers for Medicare & Medicaid Services as a Pioneer Accountable Care Organization for the formation of highly integrated teams of health professionals managing care around the patient, focusing on communication, coordination, engagement and prevention to provide higher quality care while reducing costs.
- In 2024, according to U.S. News & World Report, Montefiore Medical Center is nationally ranked in 4 adult and 3 pediatric specialties and rated high performing in 5 adult specialties and 15 procedures.
Treatment Areas
- Acute and Chronic Pain
- Aging
- Asthma
- Atrial Fibrillation
- Autism
- Cancer
- Congestive Heart Failure
- Contraception
- Dementia
- Depression
- Diabetes
- Eczema
- Genetic Diseases
- Headache/Migraine
- Healthy Volunteers
- Heart Disease
- Hidradenitis Suppurativa
- Infectious Diseases
- Inflammatory Bowel Disease
- Joint Diseases
- Kidney Disease
- Learning & Developmental Disabilities
- Liver Disease
- Lung Disease
- Lupus
- Obesity
- Obsessive Compulsive Disorder
- Opioid Use Disorder
- Psoriasis
- Respiratory Disease
- Sepsis
- Sexually Transmitted Diseases
- Sickle Cell Disease
- Sleep & Wake Disorders
- Substance Abuse and Addiction
- Transplantation
Investigator Experience
Albert Einstein College of Medicine is comprised of 2,000 faculty members with international recognition and known as prominent leaders in their respective fields. These outstanding physicians and scientists are responsible for unparalleled scientific innovation and first-class application of medicine, having published 3,211 papers in peer-reviewed journals in 2023. In an effort to synergize inter-disciplinary clinical and translational research, Einstein and Montefiore are committed to using innovative research tools and information technologies to create collaborative bridges and promote collaboration across the entire bench-to-bedside-to-population spectrum of science. The ICTR hosts its Research Profiles, powered by Elsevier to exhibit Einstein and Montefiore researchers and their research expertise.
Staff Expertise
The research staff has extensive experience in conducting clinical research projects, including but not limited to study coordination, data management, human subject protection, study monitoring, contract negotiation, budget development, regulatory oversight, clinical project management, database development, data and safety monitoring community engagement and regulatory affairs.
Other Information
Founded on the partnership between Albert Einstein College of Medicine and Montefiore Medical Center, the ICTR has helped cement collaboration in clinical and translation research since 2007. The ICTR is a member of the nationwide Clinical and Translational Science Awards (CTSA) consortium, funded by the NIH. The CTSA is designed to break down barriers that inhibit cross-disciplinary, bidirectional research from the laboratory to the clinic and back again.
The mission of the Einstein-Montefiore ICTR is to
- Improve the transfer of information from "bench-to-bedside” to better serve the community;
- Enhance community participation in research activities;
- Enhance the discipline of clinical and translational research by promoting multidisciplinary collaboration;
- Address critical barriers in research to accelerate the transition of beneficial research;
- Provide infrastructure and collaborative support; and
- Enhance training, education and career development as part of the CTSA consortium in order to improve opportunities for the development of a diverse investigator and research community.