Holy Cross Hospital Research Center (HCHRC) is a hospital-based clinical trials management division of the nationally recognized 577-bed Holy Cross Hospital in Fort Lauderdale, Florida. HCHRC conducts inpatient and outpatient clinical trials in a variety of therapeutic areas.

HCHRC provides the clinical trials infrastructure which removes roadblocks traditionally seen in inpatient studies. Success continues in the outpatient setting as HCHRC conducts clinical trials with Principal Investigators affiliated with Holy Cross Hospital. Each therapeutic area has a team of experienced employees providing consistency and quality of care.

Holy Cross Hospital Research Center conducts trials in the following therapeutic areas:

• Anesthesiology
• Cardiology
• Dermatology
• Endocrinology
• Family Medicine
• Gastroenterology
• Internal Medicine
• Nephrology
• Neurology
• OB/GYN
• Orthopedic Surgery
• Pain Management
• Pulmonary Medicine
• Radiology
• Rheumatology
• Surgery
• Women’s Health

Principal Investigators and staff have experience working with the following sponsors and contract research organizations:

• Anthera Pharmaceutical
• ANS
• Astellas Pharma US, Inc.
• Baxter
• Bioheart
• Boehringer Ingelheim
• Bristol Myers- Squibb
• Cardiogenesis
• CardioMEMS
• Cordis
• Charles River Labs
• Cook
• Covance
• CVRx
• DeCode Genetics
• Duke Clinical Research Institute
• Eli Lilly
• Ethicon
• Glaxo Smith Kline
• Guidant
• Johnson and Johnson
• The Medicines Company
• Medtronic
• Medicure
• Novum
• Nuvelo
• Parexel
• PPD, Inc.
• Quintiles
• Sanofi Aventis
• St. Jude
• Theravance, Inc.
• TIMI
• Wyeth
• Schering-Plough

HCHRC conducts both inpatient and outpatient clinical trials within the Holy Cross Hospital campus. The proximity to specialized centers within the hospital allows HCHRC access to a large volume of patients. Holy Cross Hospital treats approximately 16,200 inpatients and 140,000 outpatients each year. Holy Cross Hospital’s catheterization laboratory performs more than 1,800 cardiac catheterizations and more than 500 interventions per year. The hospital performs more than 4,200 inpatient surgical procedures and more than 4,500 outpatient surgical procedures a year.

Holy Cross Hospital is proud to have been honored by HealthGrades for the fifth year in a row as a "Distinguished Hospital Award" Recipient for Overall Clinical Excellence". In 2007 HealthGrades awarded Holy Cross as one of the TOP 50 Hospitals in the United States. In 2005, Holy Cross Hospital was rated a top 100 hospital for Geriatric Care by U.S. News and World Report.

Holy Cross Hospital Research Center is located 7 miles from the Fort Lauderdale International Airport and 3 miles from I-95. Parking is available in the on-campus parking garage and valet is available.

The Holy Cross Hospital Research Center occupies over 5,600 feet of office space with sufficient space for meetings and patient visits. Monitors have designated areas in which phone and data lines are available.

Collectively, the physicians on the medical staff at Holy Cross have served a Principal or Sub-Investigator on more than 200 clinical trials. All physicians serving as an investigator have received formal training in Good Clinical Practice and HIPAA compliance.

Alan Niederman, M.D. Medical Director, Jim Moran Heart & Vascular Research Institute

• Alfred Alvarez, MD
• George Azar, MD
• Stuart Boe, MD
• V. Alin Botoman, MD
• Gregory Bonner, MD
• Igor Chaplik, DO
• Eric Chenven, MD
• Barry Galitzer, MD
• Joel Gellman, MD
• Ali Ghahramani, MD
• Miguel Gonzalez, MD
• Jason Green, DO
• Jonathan Harris, MD
• Kenneth Herskowitz, MD
• William Leone, MD
• Moises Lichtinger, MD
• Ira Litzenblatt, MD
• Christina Mata, MD
• M. Porter McRoberts, MD
• Amjad Munim, MD
• Karan Munuswamy, MD
• Bart Musial, MD
• Ahmed Osman, MD
• Jack Peicher, MD
• Joshua Purow, MD
• Charles Russo, MD
• Martin Rosche, MD
• Michael Rush,MD
• Peter Sarbone, MD
• Martin Shansky MD
• Marcos Szeinfeld, MD
• Imad Tabry, MD
• Harish Thaker, MD
• John Wright, MD
• Philip Zilo, MD

HCHRC Investigators have dedicated clinical research coordinators and quality assurance oversight. For efficiency of budget and contract review, a financial analyst assesses all clinical trial budgets and contracts.

HCHRC employs a full time business development manager who ensures timeliness of paper work and meetings during the site selection process and is a point of contact for the sponsor throughout the study. The business development manager is also designs and implements strategies to maximize trial enrollment.

Fort Lauderdale, Florida is home to an abundance of ethnicities, races, age groups, lifestyles, and income levels. Holy Cross Hospital mirrors the diversity of the city, thus providing the support needed to market and enroll a varied group of patients from a diverse background of physicians.

Please visit our website at www.holy-cross.com

CenterWatch is listing the following trials that are actively recruiting patients at this center.

• A phase II, study to assess the safety and effect on ventricular rate of multiple oral doses of study drug in adult subjects with atrial fibrillation
• A study to evaluate treatment with SYR-619 in Subjects with Type 2 Diabetes
• Evaluate a novel compound in subjects with Occluded Central Venous Access Devices.
• Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting with Acute Coronary Syndrome.
• Study to evaluate the safety and efficacy or oral doses of an investigational medication administered during menstruation for the treatment of menorrhagia
• Treatment of Hospital Acquired Pneumonia

For more information, please contact:

Richard Brown
Administrative Director
Holy Cross Hospital Research Center
and the Jim Moran Heart & Vascular Research Institute
4875 N. Federal Hwy
Suite 700
Ft. Lauderdale, FL 33308 USA
Phone: 954-229-8573
Fax: 954-229-8597