M. Akram Khan, M.D., FACC, FSCAI is the Medical Director of North Dallas Research Associates and has extensive cardiovascular research experience spanning over the last fifteen years.

North Dallas Research Associates has been conducting clinical research trials in the McKinney, TX area for the past five years. Due to McKinney being the second largest growing city in the nation we have access to a stable and diverse patient population that is available to participate in clinical research trials.

North Dallas Research Associates is a part of Dr Khan's primary practice, Cardiac Center of Texas, which offers comprehensive treatment and testing in Diagnostic and Interventional Cardiology. Dr Khan's commitment to quality of care and good clinical practices establishes an excellent relationship with both Sponsors and CRO's enabling this site to be a high performance facility in clinically demanding and intensive cardiovascular trials. Additionally, we have established relationships with local area institutions that have qualified personnel and treatment facilities that allows us to subcontract for complex clinical trial requirements.

• Acute Coronary Syndrome
• Acute Myocardial Infarction
• Anticoagulation Therapy
• Antiplatelet Therapy
• Angina (stable and unstable)
• Atrial Fibrillation
• Cardiac Imaging
• Mitral Valve Prolapse
• Coronary Artery Disease
• Carotid Artery Disease
• Hyperlipidemia
• Dyslipidemia
• Mixed Dyslipidemia
• Hypertension
• Congestive Heart Failure
• Peripheral Vascular Disease
• Arrhythmia
• Cardiac Catheterization
• Coronary, Carotid and Femoral Stenting
• Echocardiology
• Peripheral Arterial Disease
• Nuclear Cardiology
• Pacemaker implantation and monitoring
• Transesophageal Echo
• Angioplasty
• Intermittent Claudication
• Coronary Atheroslcerotic Disease

Sponsors and CRO's we have worked with:

• AstraZeneca
• Bristol Myers Squibb
• Bayer
• KOS Pharmaceuticals
• Novartis
• Kendle
• Myogen
• Organon
• Pfizer
• PPD
• ICON
• Takeda
• Merck
• GlaxoSmithKline
• Covance
• Parexel International
• PPD Development
• Micardis
• Sapphire
• Cordis
• Boehringer Ingelheim
• Ingenix
• Eisai
• MDS Pharma Services
• United BioSource Corporation
• Abbott
• Aristotle
• Astellas

Our office is located in the McKinney Medical Arts Building in McKinney, TX. Our facility has easy access to HWY Intersate 75 and 121. Area airports are Dallas Love Field and Dallas Forth/Worth International Airport.

Our facility is modern with high tech medical equipment offering the following technology and testing capabilities:

• Nuclear CT Scan (64 Imaging)with Calcium Scoring
• Myocardial Perfusion SPECT Imaging
• Cardiolyte Exercise Stress Testing
• Electron Encounter Pulsation Therapy
• 2DEchocardiography with Color Flow Doppler
• EKG machines
• Pacemaker Clinic
• Anticoagulation Clinic
• Clia Certified Lab
• Refrigerator, Freezer and -20 freezer
• Crash Cart
• AED Defibrillator
• Remote Data Entry
• Holter and Cardiac Event Monitoring
• Antiplatelet Treatment

At local area facilities we also provide the following services:

• Coronary Angioplasty and Intervention
• Carotid Angioplasty and Intervention
• Stent Placement
• Pacemaker Implantation
• Transesophageal Echo
• Peripheral Angioplasty and Intervention
• Cardiac Catheterization

M. Akram Khan, MD, FACC, FSCAI, has been practicing cardiovascular medicine in McKinney, TX, since 1997. He completed his cardiac fellowship at Baylor Medical Center of Dallas. He was Chief of Cardiology at Medical Center of McKinney in 2005, and has been several times since 1999. He has also been Chief of Medicine at Presbyterian Hospital of Allen and has been since 2003. He is director of the peripheral vascular disease program at Medical Center of Plano. He is and has been a member of the medical executive committee for various hospitals. Dr Khan is on staff at Medical Center of Plano, Medical Center of McKinney, Centennial Medical Center in Frisco, Presbyterian Hospital of Allen, Baylor Regional Medical Center at Plano and Texas Heart Hospital of the Southwest.

Dr. Khan is also involved in research and is the Director of North Dallas Research Associates. He is the Course Director for the annual North Texas Cardovascular Conference. Dr. Khan is a member of the following organizations: Texas Medical Association, American Heart Association, International Society of Endovascular Specialists, Association of Clinical Research Professionals and a member of the Texas Medical Board Expert Physician Panel. He is a Fellow of the American College of Cardiology and the Society for Cardiac Angiography and Interventions.

Mohammad Zaim Nawaz, MD is the Co-Director for North Dallas Research Associates.  Dr Nawaz has received the majority of his training in Texas. He graduated from the University of Texas Southwestern Medical Center after completing is Internal Medicine residency training. His sub-specialty training in invasive cardiology was from Texas A&M University. Dr. Nawaz has also completed advance fellowship training in the field of Heart Failure and Transplant Cardiology from one of the premiere cardiac transplant institutions in the Midwest, the University of Wisconsin. He will be one of the few UNOS (United Network of Organ Sharing) certified transplant physicians in North Texas. His training not only adds another segment to our invasive cardiology team, but also adds a new dimension to our practice utilizing the most advanced modalities to care for chronic and critically ill patients with congestive heart failure. We are establishing a state of the art Heart Failure Clinic on our premises offering the latest care for this group o patients and also providing inpatient heart failure consultations. Dr. Nawaz has been widely published in the premiere cardiology journals, presenting in national cardiology meetings and has received the National Research Award (NRSA), an NIH sponsored training grant in Translational Cardiovascular Research.

Brenda Joslin, CCRC is the Clinical Site Director for North Dallas Research Associates. Ms. Joslin has been in the medical field for the last seventeen years with experience in Cardiology, Asthma, Allergy and Immunoglogy and Pediatrics. She has participated in clinical research for the last seven years. She assists the Medical Director with coordinating and managing administrative and clinical aspects of investigational drug, device and other research trials. In addition, she handles budget/contract negotiation, regulatory processing, patient recruitment and retention programs, and quality assurance. Ms. Joslin has experience managing Phase II through Phase IV clincal trials, acting as unblinded pharmacist in Phase II and Phase III clinical trials and is thoroughly educated in federal regulations and institutional policies. Ms Joslin has been a member and is certified through the Association for Clinical Research Professionals since 2003.

The majority of our research subjects come from the extensive patient database of approximately 10,000. Due to the increasing population of the McKinney, TX, area we have access to a large potential pool of research subjects. We strive to manage and maintain an active recruitment and retention program.

At North Dallas Research Associates we use Study Manager software to track our patient population and provide overall study management. Our site is able to use centralized IRB's and Labs for research trials. Additionally, we have experience with local IRBs to assist in outpatient trials.

CenterWatch is listing the following trials that are actively recruiting patients at this center.

• Adults with Atrial Fibrillation or Flutter needed
• If you are a man age 50 or older, or a woman age 60 or older, you may be able to participate in the ARRIVE research study.

For more information, please contact:

Brenda Joslin, CCRC
Clinical Site Director
North Dallas Research Associates
4201 Medical Center Drive, Suite 380
McKinney, TX 75069 USA
Phone: 972-562-2345
Fax: 972-529-6935
E-mail:

If you are interested in contacting this center to discuss placing a clinical trial there, please complete and send the E-mail form below. A representative from the research center will then follow up with you.

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Last updated on August 21, 2008