University of Kentucky Chandler Medical Center
C. William Balke, MD
Associate Provost for Clinical & Translational Science
Senior Associate Dean for Research
Director, UKCRO
Professor of Medicine & Physiology
Director, Institute of Molecular Medicine
University of Kentucky
800 Rose Street
MN-150, Chandler Medical Center
Lexington, KY 40536-0298

Site Marketing Contact for Information on Investigators and Research Studies:
Roxane L. Poskin
Research Coordinator-Marketing
C201KY Clinic
Lexington, KY 40536-0284 USA
Phone: 859-257-7856
Fax: 859-257-1563
E-mail:
Web Site

    

Center Overview
Clinical Research Experience
Facility Description
Staff Expertise
Patient Demographics
Other Information
Currently Enrolling Trials
Contact Information

 

Center Overview

The University of Kentucky Chandler Medical Center (UKCMC) is one the nation’s finest academic health care centers. Its vision is to be a Top-20 academic health center recognized nationally and internationally for excellence in teaching, research and patient care. Top 10 Business Plan

The University of Kentucky is achieving outstanding success in the competitive arena of research grants & contracts (see Research statistics and national rankings). Major research areas include Aging, Behavioral Health, Cancer, Drug Evaluation, Infection and Immunity, Endocrinology, Gastroenterology, Surgery, Neurosciences, Spinal Cord Injuries, and Women's Health.

Center for Clinical and Translational Science (CCTS): In 2004, the University of Kentucky convened a Research Summit to evaluate the status of clinical and translational research at the University of Kentucky. At the same time, the NIH convened a meeting of the scientific community to identify fundamental barriers to the acceleration of basic discoveries into clinical practice. One of the main barriers identified, the need for re-engineering the research enterprise nationwide, was the impetus for the Clinical and Translational Science Award (CTSA). Interestingly enough, the results of the UK’s Research Summit embodied the very essence of the NIH’s CTSA, the need to transform the clinical and translational research enterprise at the University of Kentucky.

UK’s response to this groundbreaking NIH challenge is to develop the Center for Clinical and Translational Science (CCTS). This Center will provide a centralized infrastructure consisting of key core facilities and services to help investigators, clinicians, and scholars from across the University and the Commonwealth of Kentucky to access the much needed resources to not only become educated on the conduct of clinical research, but to afford them mechanisms in which they can access a gamut of support services needed for the conduct of high quality clinical and translational research. These services will not end at the boundaries of the University of Kentucky campus, but will reach across the Commonwealth engaging greater partnership between the communities, industry, and the University. The information on this website details many of these core facilities housed within the CCTS, with links to other services at the University of Kentucky. www.ccts.uky.edu

Highlights:

  • Institutional IRB meets six (6) times each month for rapid review and approval.
  • Clinical Research Administrator negotiates only clinical trial agreements.
  • Clinical Research Organization provides administrative regulatory and/or operations support to investigators to accelerate study initiation and coordination.
  • Based on benchmarking data, study initiation averages 45 working days.
  • Dedicated inpatient and outpatient research facilities.
  • For Clinical Trial Volunteers Website
  • Faculty and staff are experienced in Phase I, II, III and IV clinical trials.
  • Investigational Drug Service maintains a secure storage, dispensing and accountability system with service available 24 hours per day.
  • Clinical research faculty and staff complete mandatory trainings and are provided with numerous education opportunities.

UKCMC encompasses the following:

UKCMC also includes world-renowned centers:

Lexington Veterans Affairs Medical Center, (VAMC):
Many faculty members at UKCMC also maintain a joint appointment at the VAMC, expanding the potential research subject base. (UKCMC and VAMC facilities are connected via a tunnel on the university campus).

  • 107 acute care beds
  • 61 nursing home beds

Patient at the VAMC in 2003:

  • 249,907 outpatient visits
  • 5,390 inpatient visits

Clinical Research Organization Center

  • University of Kentucky Clinical Research Organization, (UKCRO) was established to promote and expand the UKCMC clinical research. The UKCRO is conveniently located in the Kentucky Clinic, which is adjacent to the University of Kentucky Hospital, this 3,985 square foot facility provides ample space to conduct outpatient trials and short-term pharmacokinetic studies. General Clinical Research Center (GCRC) occupies 4,344 square foot of space in the newly remodeled Research Inpatient Clinic on the 5 floor of the hospital. These two centers along with the Delta Dental of Kentucky Clinical Research Center (DDKCRC) will build on the past success to become all encompassing service center -The Clinical Research Development and Operations Center (CR-DOC) through the Center for Clinical Translational Science (CCTS). These facilities resources are available to all clinical investigators throughout the University.

Services:

  • To promote and facilitate clinical trials
  • To provide regulatory and administrative services
  • To provide inpatient an outpatient coordination of all phase clinical trials
  • Assist faculty and provide expertise in investigator initiated projects
  • Improve and monitor clinical research compliance
  • Provide clinical research training and educational opportunities

The UK Clinical Research Organization and the General Clinical Research Center (GCRC) occupy the newly remodeled Research Outpatient Clinic. Both facilities resources are available to all clinical investigators throughout the University.

Outpatient amenities include:

  • Reception Area
  • 7 exam rooms
  • 3 capacity infusion room
  • Lab processing and shipping area with dry ice
  • 5 Individual Monitor Areas complete with remote computer hook-up
  • Administrative Offices
  • Conference Room
  • Secured Storage
  • Cold Kitchen
  • EKG
  • Access by bridge to the UK Hospital and Services
  • -70° Freezer
  • -20° Freezer
  • Emergency Cart Available
  • Refrigerated Centrifuge

Inpatient amenities include:

  • 14-bed inpatient unit
  • GCRC Laboratory
  • Metabolic Kitchen

Clinical Research Experience

Research/therapeutic areas:

To learn more about previous and ongoing clinical research at the UK Chandler Medical Center, please refer to the following page: www.mc.uky.edu/research.asp and Research 2004.

Facility Description

The University of Kentucky is centrally located in the scenic rolling hills of the Bluegrass.

(For descriptions, including photos, of some of UKCMC’s facilities, see Facilities).

The Lexington, Kentucky campus includes:

Programs and Services

Travel and Lodging Information

Hotels
Lexington Convention and Visitors Bureau
301 East Vine Street
Lexington, Kentucky 40507
1-800-845-3959
http://www.visitlex.com/accom/accommodations.html

Metrotravelguide.com
www.metrotravelguide.com

Airport
Bluegrass Airport
4000 Versailles Road
859-425-3114
www.bluegrassairport.com

Taxicab
Yellow Cab Taxicabs
859-231-8294

Campus Guide
Campus Map
www.uky.edu/CampusGuide

Staff Expertise

The UK Chandler Medical Center is supported by more than 500 faculty physicians and dentists, 400 resident physicians and a staff of 3,200 health professionals committed to high-quality patient care. It has created an appealing environment to attract, reward and retain outstanding, multi-disciplinary clinical research personnel. Coordinator certification serves as a means of advancement. More than 75% of the currently employed Clinical Research Coordinators and Clinical Research Associates are certified, with many others in the process of obtaining certification. Proactive educational and training series are offered to ensure staff knowledge, skills and compliance with good clinical practice guidelines.

Patient Demographics

Kentucky has a population of 4,173,405. The UK Chandler Medical Center provides health care to residents of all (120) Kentucky counties and surrounding states, (Kentucky and Regional Demographics). Much of the regional area is rural and consists of stable, non-transient people, with a high incidence of major chronic diseases. Patient contacts for 1998 included more than 20,000 admissions, 35,000 emergency department visits, and 368,000 outpatient visits. Disease demographics may be readily obtained for determination of potential subject pools.

Lexington, KY Community Profile.

Kentucky is in the middle of the "Coronary Valley" - a name given to areas with the highest rates of coronary heart disease.

Kentucky’s ranking in disease areas in comparison to other states in the nation:

  • 27% of adult Kentuckians smoke (KY is ranked #1 in nation)
  • 27% report no physical activities (#2)
  • 33% report not using seat beats (#3)
  • 38% are overweight; 24% are obese (#6)
  • 9% of adults are diabetic (#7)
  • 68% of individuals over the age of 65 are immunized (#11)
  • Kentucky ranks 13th nationally in premature deaths
  • 65% have a high school education (#14)
  • Kentucky ranks 32nd nationally in the adequacy of prenatal care
  • 27% of women who are pregnant continue to smoke while pregnant
  • 43% of the 411 counties in the U.S. classified as high persistent poverty counties are located in Kentucky, all among the 51 counties in Kentucky that are located in Appalachian Eastern Kentucky.
  • Cardiovascular disease in the leading cause of death in Kentucky
  • 20 counties have Chronic Heart Disease mortality rates 25% higher than the national average
  • Kentucky is ranked 3rd highest in cancer mortality rates
  • Cancer rates for Incidence and Mortality by county (source 2007 Kentucky Cancer Registry)
  • Kentucky is ranked 5th in the nation in deaths from coronary heart disease and overall cardiovascular disease
  • Kentucky is ranked 6th as one of the nation’s worst location of allergies
  • In most cases, serious health problems in Kentucky can be explained by its heavy smoking rate (one of the highest in the nation)
  • Map of Adult Kentucky Illicit Drug Use Population
  • Incidence of Mental stress, depression and emotional problems in the Adult Kentucky Population

Other Information

Other sites of interest at UK include:

For Clinical Trials Volunteer: www.mc.uky.edu/research/clinicaltrials.htm

Currently Enrolling Trials

CenterWatch is listing the following trials that are actively recruiting patients at this center.

Contact Information

For more information, please contact:


University of Kentucky Chandler Medical Center
C. William Balke, MD
Associate Provost for Clinical & Translational Science
Senior Associate Dean for Research
Director, UKCRO
Professor of Medicine & Physiology
Director, Institute of Molecular Medicine
University of Kentucky
800 Rose Street
MN-150, Chandler Medical Center
Lexington, KY 40536-0298

Site Marketing Contact for Information on Investigators and Research Studies:
Roxane L. Poskin
Research Coordinator-Marketing
C201KY Clinic
Lexington, KY 40536-0284 USA
Phone: 859-257-7856
Fax: 859-257-1563
E-mail:

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    Last updated on September 5, 2008

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