Extern Validation of a Predictive Score of Brain Death in Severe Stroke (DIAPASON1)

Inclusion Criteria:

• Patient aged 18 years and over.

• Patient with a sever stroke less than 48 hours diagnosed by brain imaging magneticresonance imaging or computed tomography (including cerebral infarction,intra-parenchymal hemorrhage and subarachnoid haemorrhage

• Patient with Glasgow Scale score <8 Engaged vital prognosis

• Absence of therapeutic resources

• Decision of resuscitation measures to protect the organs in the purpose organ donationafter brain death

Exclusion Criteria:

• Pregnant woman

• Patient with recent traumatic brain injuries (subdural hematoma, extradural hematomaand contusions)

• Obvious contraindication of organ donation excluding the patient from organ protectionmeasures in intensive care unit (expression of patient opposition, HIV infection,active tuberculosis, spongiform encephalopathy,

• human growth hormones treatment origin, rabies, active cancer)

• Opposition of family member of the patient