Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy.

Last updated: February 11, 2025
Sponsor: Nazmy Edward Seif
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anesthesia

Treatment

Low-Thoracic Epidural Anesthesia

General Anesthesia

Clinical Study ID

NCT04546230
LTEALN
  • Ages 18-70
  • All Genders

Study Summary

Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay, earlier return to work and daily life activities, a more favourable cosmetic result and outcomes similar to that of open surgery.

Recently, advanced laparoscopic surgery has targeted older and high risk patients for general anesthesia; in these patients, regional anesthesia offers several advantages with improved patient satisfaction. Compared with alternative anesthetic techniques, epidural anesthesia may reduce the risks of venous thromboembolism, myocardial infarction, bleeding complications, pneumonia, respiratory depression and renal failure.

The aim of this study is to compare the conventional general anesthetic technique to the regional anesthesia for laparoscopic nephrectomy, in modified lateral decubitus position using low-pressure pneumoperitoneum.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • ASA I - II.

  • Adult patients scheduled for laparoscopic nephrectomy.

Exclusion

Exclusion Criteria:

  • Patient refusal.

  • Contraindication to regional anesthesia (e.g., coagulopathy, site infection).

  • Allergy to local anesthetics.

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: Low-Thoracic Epidural Anesthesia
Phase:
Study Start date:
September 19, 2020
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • Cairo University Hospitals

    Cairo,
    Egypt

    Active - Recruiting

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