Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

Last updated: November 3, 2023
Sponsor: Henry Ford Health System
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carpal Tunnel Syndrome

Treatment

Corticosteroid injections for CTS treatment

Clinical Study ID

NCT04737239
14552
  • Ages > 18
  • All Genders

Study Summary

Carpal Tunnel Syndrome (CTS) is the most common nerve entrapment syndrome worldwide. There are currently no studies examining the effectiveness of corticosteroid injections in patients with normal (negative) EMG studies. The purpose of this study is to gain a better understanding of the duration of symptom improvement post corticosteroid injection in patients with negative or mild EMG studies. The Boston Carpal Tunnel Questionnaire will be given to patients undergoing corticosteroid injections for the treatment of carpal tunnel syndrome to assess their response to the injection. Investigators will collect data retrospectively. The Boston Carpal Tunnel Questionnaire (BCTQ) is administered as per standard protocol to all patients with CTS who have a negative or mild EMG study. The BCTQ assesses the patient's self-reported symptom severity and functional status. Investigators will analyze this data with respect to demographics as well as numbness in the median n. distribution, nocturnal numbness, weakness/atrophy of the thenar musculature, Tinel's sign, Phalen's test, loss of 2-point discrimination, Quick-Dash score, and grip strength score.

The primary outcome will be the Boston Carpal Tunnel Questionnaire outcome score under the different EMG conditions.The secondary outcomes will be numbness in the median n. distribution, nocturnal numbness, weakness/atrophy of the thenar musculature, Tinel's sign, Phalen's test, loss of 2-point discrimination, QuickDash score, and grip strength score. Both outcomes will be examined in patients with negative or mild EMG readings. This information will allow orthopedic physicians to gain a better understanding of the duration of symptom improvement post-corticosteroid injection, allowing them to fine tune their treatment plans for CTS patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients who speak English
  • Patients who are 18 years or older
  • Patients who are clinically diagnosed with CTS
  • Patients who have a negative or mild EMG study
  • Patients who receive a corticosteroid injection after obtaining a negative or mild EMGstudy

Exclusion

Exclusion Criteria:

  • Patients who do not speak English
  • Patients who are younger than 18 years of age
  • Patients who have experienced previous trauma to the wrist
  • Patients who have had previous treatment for CTS including but not limited tocorticosteroid injection or surgery
  • Patients with a moderate or severe EMG study

Study Design

Total Participants: 300
Treatment Group(s): 1
Primary Treatment: Corticosteroid injections for CTS treatment
Phase:
Study Start date:
December 23, 2020
Estimated Completion Date:
December 22, 2024

Connect with a study center

  • Henry Ford Health System

    Detroit, Michigan 48202
    United States

    Active - Recruiting

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