Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.

Key Inclusion Criteria:

• Males and females, 46 years of age or older

• A diagnosis of primary open-angle glaucoma, who are candidates for medical therapy,laser treatment, or glaucoma-filtering surgery

• Pseudophakic with prior uncomplicated cataract surgery

Key Exclusion Criteria:

• Angle closure, congenital, or secondary glaucoma

• Diagnosed degenerative visual disorders

• Clinically significant intraocular inflammation or infection