Real World Study of MPM in China

Last updated: September 5, 2021
Sponsor: Chinese Academy of Medical Sciences
Overall Status: Active - Recruiting

Phase

N/A

Condition

Mesothelioma

Cancer

Treatment

N/A

Clinical Study ID

NCT05042557
NCC202062402
  • Ages > 18
  • All Genders

Study Summary

Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with atypical clinical manifestations. Most patients with MPM are at an advanced stage at the time of diagnosis, and only a few patients can be cured by radical surgery and other treatment measures. Pemetrexed

  • cisplatin chemotherapy with or without bevacizumab is still the standard treatment for MPM. In recent years, multimodality therapy including surgery, radiotherapy and chemotherapy have shown certain advantages in improving patient overall survival time. Targeted and immunotherapy may bring breakthroughs in MPM therapy. However, there are still no high-quality evidence-based medical evidence reports on the treatment model and effects of MPM patients in China.

Focusing on MPM, we plan to systematically review the relevant scientific literature, confirm relevant scientific research questions, and provide references for related treatments. On this basis, we will estimate MPM incidence and mortality rates from 2014 to 2025 based on the data published by the National Cancer Registry. Meanwhile, a retrospective study cohort was constructed based on the electronic medical record database, and according to the research demand, patients were followed up with their post-discharge survival status to comprehensively describe and analyze the incidence, diagnosis, treatment, and prognosis of MPM patients. Also, exploratory analysis of the therapeutic effects of existing clinical treatments was conducted.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Pathologically confirmed as malignant pleural mesothelioma
  • Aged over 18

Exclusion

Exclusion Criteria:

  • Follow-up less than 3 months

Study Design

Total Participants: 500
Study Start date:
June 01, 2021
Estimated Completion Date:
December 20, 2022

Connect with a study center

  • National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

    Beijing, 100021
    China

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.