Colonisation Efficacy of Oral Probiotic Fast Melt Powder

Last updated: May 5, 2022
Sponsor: BLIS Technologies Limited
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05367518
BLTCT2022/1
  • Ages 18-80
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

To evaluate the colonisation efficacy (i.e. ability of the probiotic bacteria to remain in your mouth) of a fast melt powder that quickly dissolves in the mouth. The fast melt powder will contain a Streptococcus salivarius probiotic and the study is to be done in healthy adults.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. In general good health 18 - 80 years of age.
  2. Practice good oral hygiene.

Exclusion

Exclusion Criteria:

  1. Have a history of autoimmune disease or are immunocompromised.
  2. Are on concurrent antibiotic therapy or regular antibiotic use within last 1 week
  3. History of allergy (e.g. dairy).

Study Design

Total Participants: 20
Study Start date:
May 15, 2022
Estimated Completion Date:
June 30, 2022

Study Description

This is a double-blind, randomized controlled study with no cross over to evaluate the colonization efficacy of fast melt powders containing a commercially available probiotic bacterium Streptococcus salivarius K12.

Participants will be randomly assigned to one of the 2 groups consuming Fast Melt powder containing two different doses of Streptococcus salivarius K12 over a seven day period. Saliva samples will be collected at predetermined time points pre and post intervention. Colonization efficacy will be determined by enumerating the probiotic in the saliva samples using standard microbiological techniques.

Connect with a study center

  • Blis Technologies Ltd

    Dunedin, Otago 9012
    New Zealand

    Active - Recruiting

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