Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE)

Last updated: September 30, 2022
Sponsor: Uppsala University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Benign Prostatic Hyperplasia (Enlarged Prostate)

Prostate Disorders

Treatment

N/A

Clinical Study ID

NCT05531240
276725
  • Ages > 45
  • Male

Study Summary

This study focuses on the treatment of benign prostatic hyperplasia which causes lower urinary tract symptoms.

The purpose of the research project is to evaluate PAE in terms of both medical and health economic outcomes. To evaluate whether there are any differences in effect (IPSS), complications, costs and perceived quality of life compared with TUR-P.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Benign prostatic hyperplasia where medical treatment has not helped or for otherreasons has not been deemed applicable
  • IPSS>=8
  • Prostate volume [40-80] ml measured via transrectal ultrasound
  • Peak flow rate (Qmax) <= 15 ml / s,
  • Verified obstruction by urodynamic studies (cystometry)
  • Surgery not contraindicated

Exclusion

Exclusion Criteria:

  • Prostate cancer
  • Severe atherosclerosis
  • Kidney failure
  • Urethral stricture
  • Active cystitis or prostatitis
  • Bladder stone.
  • Neurogenic bladder disorder
  • Contrast product allergy

Study Design

Total Participants: 104
Study Start date:
October 01, 2022
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • Helsingborgs Hospital

    Helsingborg, Region Skånes 252 23
    Sweden

    Site Not Available

  • Mälarsjukhuset

    Eskilstuna, Region Sörmland 633 49
    Sweden

    Site Not Available

  • Lasarettet i Enköping

    Enköping, Region Uppsala 745 38
    Sweden

    Site Not Available

  • Region Vastmanland Hospital

    Västerås, Västmanland 721 89
    Sweden

    Active - Recruiting

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