A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Last updated: April 2, 2025
Sponsor: Janssen Research & Development, LLC
Overall Status: Active - Recruiting

Phase

3

Condition

Multiple Myeloma

Platelet Disorders

Cancer

Treatment

Talquetamab

Dexamethasone

Teclistamab

Clinical Study ID

NCT05552222
CR109237
2022-000909-28
64007957MMY3005
2023-503442-30-00
  • Ages > 18
  • All Genders

Study Summary

The purpose of this study is to compare the efficacy of teclistamab in combination with daratumumab and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab and lenalidomide (Tal-DR) versus daratumumab, lenalidomide, dexamethasone (DRd).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Have a diagnosis of multiple myeloma according to the International Myeloma WorkingGroup (IMWG) diagnostic criteria

  • Be newly diagnosed and not considered a candidate for high-dose chemotherapy withautologous stem cell transplant (ASCT) due to: ineligible due to advanced age OR;ineligible due to the presence of comorbid condition(s) likely to have a negativeimpact on tolerability of high-dose chemotherapy with ASCT OR; deferral of high-dosechemotherapy with ASCT as initial treatment

  • Have an Eastern Cooperative Oncology Group (ECOG) performance status score of 0 to 2

  • A participant must agree not to be pregnant, breastfeeding, or planning to becomepregnant while enrolled in this study or within 6 months after the last dose ofstudy treatment

  • A participant must agree not to plan to father a child while enrolled in this studyor within 100 days after the last dose of study treatment

Exclusion

Exclusion Criteria:

  • Received any prior therapy for multiple myeloma or smoldering myeloma other than ashort course of corticosteroids (not to exceed total of 160 milligrams [mg]dexamethasone or equivalent). In addition, received a cumulative dose of systemiccorticosteroids equivalent to greater than or equals to (>=) 20 mg of dexamethasonewithin 14 days before randomization

  • Had plasmapheresis within 28 days of randomization

  • Had a stroke, transient ischemic attack, or seizure within 6 months prior torandomization

  • Known allergies, hypersensitivity, or intolerance to teclistamab or talquetamabexcipients

  • Known contraindications to the use of daratumumab or lenalidomide per localprescribing information

  • Myeloma Frailty Index of >=2 with the exception of participants who have a score of 2 based on age alone

Study Design

Total Participants: 1590
Treatment Group(s): 5
Primary Treatment: Talquetamab
Phase: 3
Study Start date:
October 25, 2022
Estimated Completion Date:
October 28, 2033

Connect with a study center

  • Royal Prince Alfred Hospital

    Camperdown, 2050
    Australia

    Active - Recruiting

  • Barwon Health - University Hospital Geelong

    Geelong, 3220
    Australia

    Active - Recruiting

  • Liverpool Hospital

    Liverpool, 2170
    Australia

    Active - Recruiting

  • Fiona Stanley Hospital

    Murdoch, 6150
    Australia

    Site Not Available

  • Sir Charles Gairdner Hospital

    Nedlands, 6009
    Australia

    Active - Recruiting

  • Calvary Mater Newcastle Hospital

    New South Wales, 2298
    Australia

    Active - Recruiting

  • Wollongong Hospital

    Wollongong, 2500
    Australia

    Active - Recruiting

  • Princess Alexandra Hospital

    Woolloongabba, 4102
    Australia

    Active - Recruiting

  • Ordensklinikum Linz GmbH Elisabethinen

    Linz, 4020
    Austria

    Active - Recruiting

  • LKH - Universitätsklinikum der PMU Salzburg

    Salzburg, 5020
    Austria

    Site Not Available

  • SCRI CCCIT gem GmbH

    Salzburg, 5020
    Austria

    Active - Recruiting

  • Medical University Vienna

    Vienna, 1090
    Austria

    Active - Recruiting

  • Hanusch Krankenhaus

    Wien, 1140
    Austria

    Active - Recruiting

  • Institut Jules Bordet

    Anderlecht, 1070
    Belgium

    Active - Recruiting

  • Ghent University Hospital

    Gent, 9000
    Belgium

    Active - Recruiting

  • Jolimont

    Haine Saint Paul La Louviere, 7100
    Belgium

    Completed

  • Jolimont

    Haine-Saint-Paul, La Louviere, 7100
    Belgium

    Site Not Available

  • Az Groeninge

    Kortrijk, 8500
    Belgium

    Active - Recruiting

  • Universitair Ziekenhuis Leuven

    Leuven, 3000
    Belgium

    Active - Recruiting

  • GZA Ziekenhuizen- Campus St Augustinus

    Wilrijk, 2610
    Belgium

    Completed

  • Fundacao Pio XII

    Barretos, 14784 400
    Brazil

    Active - Recruiting

  • Santa Casa de Misericordia de Belo Horizonte

    Belo Horizonte, 30150 320
    Brazil

    Active - Recruiting

  • Santa Casa de Misericordia de Belo Horizonte

    Belo Horizonte, Minas Gerais, 30150-221
    Brazil

    Site Not Available

  • Liga Paranaense de Combate ao Cancer

    Curitiba, 81520 060
    Brazil

    Active - Recruiting

  • Instituto Do Cancer Do Ceara

    Fortaleza, 60430-230
    Brazil

    Active - Recruiting

  • Liga Norte Riograndense Contra O Cancer

    Natal, 59062-000
    Brazil

    Active - Recruiting

  • Complexo Hospitalar de Niteroi

    Niteroi, 24030-103
    Brazil

    Active - Recruiting

  • Complexo Hospitalar de Niterói

    Niteroi, 24030-103
    Brazil

    Site Not Available

  • Hospital De Clinicas De Porto Alegre

    Porto Alegre, 90035 903
    Brazil

    Active - Recruiting

  • Hospital de Clinicas de Porto Alegre

    Porto Alegre, 90035-903
    Brazil

    Active - Recruiting

  • Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP

    Ribeirao Preto, 14051-140
    Brazil

    Active - Recruiting

  • Hospital das Clínicas da Faculdade de Medicina de RPUSP - HCRP

    Ribeirao Preto, 14048-900
    Brazil

    Site Not Available

  • Hospital das Clínicas da Faculdade de Medicina de RPUSP - HCRP

    Ribeirão Preto, 14048-900
    Brazil

    Site Not Available

  • Hospital Sao Rafael

    Salvador, 41235-190
    Brazil

    Active - Recruiting

  • Clinica Medica Sao Germano S/S LTDA

    Sao Paulo, 04537-081
    Brazil

    Active - Recruiting

  • Hospital Das Clinicas Da Faculdade De Medicina Da USP

    Sao Paulo, 05403 000
    Brazil

    Active - Recruiting

  • Hospital Nove de Julho

    Sao Paulo, 01409-902
    Brazil

    Active - Recruiting

  • Clinica Sao Germano

    São Paulo, 01455-010
    Brazil

    Site Not Available

  • Arthur J E Child Comprehensive Cancer Centre

    Calgary, Alberta T2N 5G2
    Canada

    Active - Recruiting

  • Arthur J. E. Child Comprehensive Cancer Centre

    Calgary, Alberta T2N 5G2
    Canada

    Active - Recruiting

  • Tom Baker Cancer Center University of Calgary

    Calgary, Alberta T2N 4N2
    Canada

    Active - Recruiting

  • Tom Baker Cancer Center, University of Calgary

    Calgary, Alberta T2N 4N2
    Canada

    Site Not Available

  • Cross Cancer Institute

    Edmonton, Alberta T6G 1Z2
    Canada

    Active - Recruiting

  • British Columbia Cancer Agency

    Vancouver, British Columbia V5Z4E6
    Canada

    Active - Recruiting

  • Juravinski Cancer Centre

    Hamilton, Ontario L8V5C2
    Canada

    Site Not Available

  • The Ottawa Hospital - General Campus

    Ottawa, Ontario K1H 8L6
    Canada

    Site Not Available

  • CHU de Quebec L Hotel Dieu de Quebec

    Quebec, G1J 1Z4
    Canada

    Active - Recruiting

  • CHU de Québec Université Laval

    Quebec, G1R 2J6
    Canada

    Site Not Available

  • Beijing Tongren Hospital CMU

    Beijing, 100051
    China

    Active - Recruiting

  • Peking Union Medical College Hospital

    Beijing, 100006
    China

    Active - Recruiting

  • Peking University First Hospital

    Beijing, 100034
    China

    Active - Recruiting

  • Changzhou No 2 Peoples Hospital

    Chang Zhou, 213004
    China

    Active - Recruiting

  • The First Hospital of Jilin University

    Changchun, 130061
    China

    Active - Recruiting

  • The Second Xiangya Hospital of Central South Hospital

    Changsha, 410011
    China

    Active - Recruiting

  • Beijing Chaoyang Hospital

    Chaoyang District, 100020
    China

    Active - Recruiting

  • Sichuan Provincial People's Hospital

    Chengdu, 610072
    China

    Site Not Available

  • Sichuan Provincial Peoples Hospital

    Chengdu, 610072
    China

    Active - Recruiting

  • Chongqing University Cancer Hospital

    Chongqing, 400030
    China

    Active - Recruiting

  • Fujian Meidical University Union Hospital

    Fu Zhou, 350001
    China

    Active - Recruiting

  • Nanfang Hospital

    Guangzhou, 510515
    China

    Active - Recruiting

  • Sun Yat -Sen University Cancer Center

    Guangzhou, 511363
    China

    Active - Recruiting

  • First Affiliated Hospital, Medical School of Zhejiang University

    Hang Zhou, 310009
    China

    Site Not Available

  • The Second Affiliated Hospital of Zhejiang University

    Hang Zhou, 310003
    China

    Active - Recruiting

  • No.1 Affiliated Hospital, Medical College of Zhejiang University

    Hangzhou, 310003
    China

    Active - Recruiting

  • Harbin medical university cancer hospital

    Harbin, 150081
    China

    Active - Recruiting

  • Qilu Hospital of Shandong University

    Jinan, 250012
    China

    Active - Recruiting

  • Zhongda Hospital Southeast University

    Nan Jing, 214135
    China

    Active - Recruiting

  • The First Affiliated Hospital of Guangxi Medical University

    Nan Ning Shi, 530021
    China

    Active - Recruiting

  • The First Affliated Hospital Of Nanchang University

    Nanchang, 330006
    China

    Active - Recruiting

  • Nanjing Drum Tower Hospital

    Nanjing, 210008
    China

    Active - Recruiting

  • Renji Hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, 200127
    China

    Active - Recruiting

  • Ruijin Hospital Shanghai Jiao Tong University

    Shanghai, 200025
    China

    Active - Recruiting

  • Ruijin Hospital, Shanghai Jiao Tong University

    Shanghai, 200025
    China

    Site Not Available

  • Shanghai Fourth People s Hospital

    Shanghai, 200434
    China

    Active - Recruiting

  • Peking University Shenzhen Hospital

    Shen Zhen Shi, 518036
    China

    Active - Recruiting

  • Shengjing Hospital Of China Medical University

    Shenyang, 110022
    China

    Active - Recruiting

  • Shengjing Hospital of China Medical University

    Shenyang, 110055
    China

    Site Not Available

  • Institute of Hematology & Blood Diseases Hospital

    Tian Jin, 300020
    China

    Site Not Available

  • Institute of Hematology and Blood Diseases Hospital

    Tian Jin, 300020
    China

    Active - Recruiting

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, 300060
    China

    Active - Recruiting

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, 325000
    China

    Active - Recruiting

  • Wuhan Tongji Hospital Tongji Medical College

    WuHan, 430032
    China

    Active - Recruiting

  • The Second Affiliated Hospital of Xi'an Jiaotong University

    Xi' An, 710004
    China

    Active - Recruiting

  • The first affiliated hospital of xiamen university

    Xiamen, 361003
    China

    Active - Recruiting

  • Henan Cancer Hospital

    Zhengzhou, 450008
    China

    Active - Recruiting

  • Fakultni nemocnice Brno

    Brno, 625 00
    Czechia

    Site Not Available

  • Fakultni nemocnice Brno

    Brno - Bohunice, 625 00
    Czechia

    Active - Recruiting

  • Fakultni nemocnice Hradec Kralove

    Hradec Kralove, 500 05
    Czechia

    Active - Recruiting

  • Fakultni nemocnice Olomouc

    Olomouc, 779 00
    Czechia

    Active - Recruiting

  • Fakultní nemocnice Olomouc

    Olomouc, 779 00
    Czechia

    Site Not Available

  • Fakultni Nemocnice Ostrava

    Ostrava, 708 52
    Czechia

    Active - Recruiting

  • Fakultni nemocnice Plzen

    Plzen, 304 60
    Czechia

    Active - Recruiting

  • VFN v Praze

    Praha, 128 08
    Czechia

    Active - Recruiting

  • Aalborg University Hospital

    Aalborg, 9000
    Denmark

    Active - Recruiting

  • Regionshospitalet Godstrup

    Herning, 7400
    Denmark

    Active - Recruiting

  • Regionshospitalet Gødstrup

    Herning, 7400
    Denmark

    Site Not Available

  • Zealand University Hospital

    Roskilde,
    Denmark

    Active - Recruiting

  • Vejle Sygehus

    Vejle, 7100
    Denmark

    Active - Recruiting

  • Helsinki University Hospital

    Helsinki, 00029 HUS
    Finland

    Site Not Available

  • Oulu University Hospital

    Oulu, 90220
    Finland

    Site Not Available

  • Turku University Hospital

    Turku, 20520
    Finland

    Site Not Available

  • APHP - Hopital Henri Mondor

    Creteil, 94010
    France

    Active - Recruiting

  • CHU Dijon

    Dijon, 21000
    France

    Site Not Available

  • Hopital Claude Huriez

    Lille, 59000
    France

    Active - Recruiting

  • CHU Nantes

    Nantes, 44093
    France

    Active - Recruiting

  • CHU Hopital Saint Antoine

    PARIS cedex 12, 75012
    France

    Active - Recruiting

  • CHU Hôpital Saint Antoine

    PARIS cedex 12, 75012
    France

    Site Not Available

  • CHU de Bordeaux - Hospital Haut-Leveque

    Pessac cedex, 33604
    France

    Active - Recruiting

  • CHU Lyon Sud

    Pierre-Benite, 69310
    France

    Active - Recruiting

  • CHU Poitiers - Hopital la Miletrie

    Poitiers, 86021
    France

    Active - Recruiting

  • CHU Poitiers - Hôpital la Milétrie

    Poitiers, 86021
    France

    Site Not Available

  • CHU de Rennes - Hopital Pontchaillou

    Rennes, 35033
    France

    Active - Recruiting

  • Institut de Cancerologie Strasbourg Europe ICANS

    Strasbourg, 67200
    France

    Active - Recruiting

  • Institut Universitaire du Cancer Toulouse Oncopole

    Toulouse, 31000
    France

    Active - Recruiting

  • Helios Kliniken Berlin Buch Gmbh

    Berlin, 13125
    Germany

    Active - Recruiting

  • St. Johannes-Hospital

    Dortmund, 44137
    Germany

    Site Not Available

  • Universitaetsklinikum Halle Saale

    Halle (Saale), 06120
    Germany

    Active - Recruiting

  • Universitaetsklinik Hamburg-Eppendorf

    Hamburg, 20251
    Germany

    Active - Recruiting

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz

    Mainz, 55131
    Germany

    Site Not Available

  • Klinikum Nuernberg Nord

    Nuernberg, 90419
    Germany

    Active - Recruiting

  • Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,

    Tübingen, 72076
    Germany

    Active - Recruiting

  • Universitaetsklinikum Wuerzburg

    Wurzburg, 97080
    Germany

    Active - Recruiting

  • Universitaetsklinikum Wuerzburg

    Würzburg, 97080
    Germany

    Site Not Available

  • Alexandra General Hospital of Athens

    Athens Attica, 115 28
    Greece

    Active - Recruiting

  • Anticancer Hospital of Thessaloniki 'Theageneio'

    Thessaloniki, 546 39
    Greece

    Site Not Available

  • Anticancer Hospital of Thessaloniki Theageneio

    Thessaloniki, 546 39
    Greece

    Active - Recruiting

  • 'G. Papanikolaou' Hospital of Thessaloniki

    Thessalonikis, 570 10
    Greece

    Site Not Available

  • G Papanikolaou Hospital of Thessaloniki

    Thessalonikis, 570 10
    Greece

    Active - Recruiting

  • Semmelweis Egyetem

    Budapest, 1088
    Hungary

    Site Not Available

  • Pecsi Tudomanyegyetem Klinikai Kozpont

    Pécs, 7624
    Hungary

    Site Not Available

  • M S Ramaiah Medical College and Hospital

    Bangalore, 560054
    India

    Site Not Available

  • Tata Memorial Hospital

    Bombay, 400012
    India

    Site Not Available

  • Post Graduate Institute of Medical Education & Research (PGIMER)

    Chandigarh, 160012
    India

    Site Not Available

  • Fortis Memorial Research Institute

    Gurugram, 122002
    India

    Site Not Available

  • Bhagwan Mahaveer Hospital & Research Centre

    Jaipur, 302017
    India

    Site Not Available

  • Tata Medical Center

    Kolkata, 700160
    India

    Site Not Available

  • Kingsway Hospital

    Nagpur, 440001
    India

    Site Not Available

  • All India Institute of Medical Sciences

    New Delhi, 110029
    India

    Site Not Available

  • Jawaharlal Institute of Postgraduate Medical Education and Research

    Pondicherry, 605008
    India

    Site Not Available

  • Deenanath Mangeshkar Hospital and Research Centre

    Pune, 411004
    India

    Site Not Available

  • Rambam Medical Center

    Haifa, 3109601
    Israel

    Active - Recruiting

  • Shaare Zedek Medical Center

    Jerusalem, 9103102
    Israel

    Active - Recruiting

  • Rabin

    Petah Tikva, 49100
    Israel

    Active - Recruiting

  • Sheba Medical Center

    Ramat Gan, 52621
    Israel

    Active - Recruiting

  • Tel Aviv Sourasky Medical Center

    Tel Aviv Yafo, 6423906
    Israel

    Active - Recruiting

  • ASST Papa Giovanni XXIII Bergamo

    Bergamo, 24127
    Italy

    Active - Recruiting

  • A O U Sant Orsola Malpighi

    Bologna, 40138
    Italy

    Active - Recruiting

  • A.O.U Sant'Orsola-Malpighi

    Bologna, 40138
    Italy

    Active - Recruiting

  • Careggi University Hospital

    Firenze, 50134
    Italy

    Active - Recruiting

  • Ospedale San Raffaele

    Milan, 20132
    Italy

    Active - Recruiting

  • Azienda Ospedaliera di Rilievo Nazionale A Cardarelli

    Naples, 80131
    Italy

    Active - Recruiting

  • IRCCS Policlinico San Matteo, Università degli studi di Pavi

    Pavia, 27100
    Italy

    Active - Recruiting

  • Universita Degli Studi di Roma 'Tor Vergata'

    Roma, 00133
    Italy

    Site Not Available

  • Universita Degli Studi di Roma Tor Vergata

    Roma, 00133
    Italy

    Active - Recruiting

  • Istituto Clinico Humanitas

    Rozzano, 20089
    Italy

    Active - Recruiting

  • Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino

    Torino, 10126
    Italy

    Active - Recruiting

  • Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino

    Torino, 10126
    Italy

    Active - Recruiting

  • Juntendo University Hospital

    Bunkyo Ku, 113 8431
    Japan

    Active - Recruiting

  • Juntendo University Hospital

    Bunkyo-Ku, 113-8431
    Japan

    Site Not Available

  • Chiba Cancer Center

    Chiba, 260 0801
    Japan

    Active - Recruiting

  • Kameda General Hospital

    Chiba, 296-0041
    Japan

    Site Not Available

  • Kameda Medical Center

    Chiba, 296-0041
    Japan

    Active - Recruiting

  • National Hospital Organization Mito Medical Center

    Higashiibaraki-gun, 311-3193
    Japan

    Active - Recruiting

  • Kansai Medical University Hospital

    Hirakata, 573-1191
    Japan

    Active - Recruiting

  • Hyogo Medical University Hospital

    Hyôgo, 663-8501
    Japan

    Active - Recruiting

  • Saitama Medical University Hospital

    Iruma-gun, 350-0495
    Japan

    Active - Recruiting

  • Tokai University Hospital

    Kanagawa, 259-1193
    Japan

    Active - Recruiting

  • Kanazawa University Hospital

    Kanazawa, 920 8641
    Japan

    Active - Recruiting

  • Kumamoto University Hospital

    Kumamoto-shi, 860-8556
    Japan

    Active - Recruiting

  • Matsuyama Red Cross Hospital

    Matsuyama-City, 790-8524
    Japan

    Active - Recruiting

  • National Hospital Organization Nagasaki Medical Center

    Nagasaki, 856-8562
    Japan

    Active - Recruiting

  • National Hospital Organization Okayama Medical Center

    Okayama, 701-1192
    Japan

    Active - Recruiting

  • Osaka Metropolitan University Hospital

    Osaka, 545 8586
    Japan

    Active - Recruiting

  • National Hospital Organization Hokkaido Cancer Center

    Sapporo, 003-0804
    Japan

    Active - Recruiting

  • Hokkaido University Hospital

    Sapporo-shi, 060-8648
    Japan

    Site Not Available

  • National Hospital Organization Shibukawa Medical Center

    Shibukawa, 377-0280
    Japan

    Active - Recruiting

  • Japanese Red Cross Medical Center

    Shibuya-ku, 150-8935
    Japan

    Active - Recruiting

  • Shizuoka Cancer Center

    Sunto Gun, 411 8777
    Japan

    Active - Recruiting

  • Shizuoka Cancer Center

    Sunto-gun, 411-8777
    Japan

    Site Not Available

  • Fujita Health University Hospital

    Toyoake, 470-1192
    Japan

    Active - Recruiting

  • Yamagata University Hospital

    Yamagata, 990 2331
    Japan

    Active - Recruiting

  • Yamanashi Prefectural Central Hospital

    Yamanashi, 400-8506
    Japan

    Active - Recruiting

  • Dong-A University Hospital

    Busan, 49201
    Korea, Republic of

    Active - Recruiting

  • Pusan National University Hospital

    Busan, 49241
    Korea, Republic of

    Active - Recruiting

  • Kyungpook National University Hospital

    Daegu, 41944
    Korea, Republic of

    Active - Recruiting

  • National Cancer Center

    Goyang si, 10408
    Korea, Republic of

    Active - Recruiting

  • National Cancer Center

    Goyang-si, 10408
    Korea, Republic of

    Site Not Available

  • Chonnam National University Hwasun Hospital

    Hwasun, 58128
    Korea, Republic of

    Active - Recruiting

  • Gachon University Gil Medical Center

    Incheon, 21565
    Korea, Republic of

    Active - Recruiting

  • Asan Medical Center

    Seoul, 05505
    Korea, Republic of

    Active - Recruiting

  • Samsung Medical Center

    Seoul, 06351
    Korea, Republic of

    Active - Recruiting

  • Seoul National University Hospital

    Seoul, 03080
    Korea, Republic of

    Active - Recruiting

  • Severance Hospital Yonsei University Health System

    Seoul, 03722
    Korea, Republic of

    Active - Recruiting

  • The Catholic University of Korea Seoul St Mary s Hospital

    Seoul, 06591
    Korea, Republic of

    Active - Recruiting

  • VUMC Amsterdam

    Amsterdam, 1081 HV
    Netherlands

    Active - Recruiting

  • Gelre Ziekenhuis

    Apeldoorn, 7334 DZ
    Netherlands

    Active - Recruiting

  • Reinier de Graaf Gasthuis

    Delft, 2625 AD
    Netherlands

    Active - Recruiting

  • St. Antonius Ziekenhuis Nieuwegein

    Nieuwegein, 3435 CM
    Netherlands

    Active - Recruiting

  • Zuyderland Medical Center

    Sittard, 6130 MB
    Netherlands

    Site Not Available

  • Zuyderland Medical Center

    Sittard-Geleen, 6162 BG
    Netherlands

    Active - Recruiting

  • Oslo University Hospital HF Ulleval sykehus

    Oslo, 0450
    Norway

    Active - Recruiting

  • Oslo University Hospital HF Ullevål sykehus

    Oslo, 0450
    Norway

    Site Not Available

  • St. Olavs Hospital

    Trondheim, 7030
    Norway

    Active - Recruiting

  • Wojewodzki Szpital Kliniczny w Bialej Podlaskiej

    Biala Podlaska, 21 500
    Poland

    Active - Recruiting

  • Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza

    Brzozow, 36-200
    Poland

    Active - Recruiting

  • Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im. Ks. B. Markiewicza

    Brzozow, 36-200
    Poland

    Site Not Available

  • Szpital Uniwersytecki nr 2 im. Jana Biziela w Bydgoszczy

    Bydgoszcz, 85-168
    Poland

    Active - Recruiting

  • Centrum Medyczne Pratia Katowice

    Katowice, 40-081
    Poland

    Site Not Available

  • Pratia Onkologia Katowice

    Katowice, 40 519
    Poland

    Active - Recruiting

  • Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach

    Kielce, 25 734
    Poland

    Active - Recruiting

  • Szpital Uniwersytecki w Krakowie

    Krakow, 30-501
    Poland

    Site Not Available

  • Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im M Kopernika w Lodzi

    Lodz, 93 513
    Poland

    Active - Recruiting

  • Centrum Onkologii Ziemi Lubelskiej im sw Jana z Dukli

    Lublin, 20 090
    Poland

    Active - Recruiting

  • Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli

    Lublin, 20-090
    Poland

    Active - Recruiting

  • SPZOZ Ministerstwa Spraw Wewnętrznych z Warminsko-Mazurskim Centrum Onkologii w Olsztynie

    Olsztyn, 10-228
    Poland

    Site Not Available

  • Uniwersytecki Szpital Kliniczny w Poznaniu

    Poznan, 60-569
    Poland

    Active - Recruiting

  • Specjalistyczny Szpital Miejski

    Toruń, 87-100
    Poland

    Site Not Available

  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy

    Warszawa, 02-781
    Poland

    Site Not Available

  • Szpital Uniwersytecki im Karola Marcinkowskiego w Zielonej Gorze

    Zielona Gora, 65 046
    Poland

    Active - Recruiting

  • Hosp. Garcia de Orta

    Almada, 2805-267
    Portugal

    Site Not Available

  • Ccab - Hosp. de Braga

    Braga, 4710-243
    Portugal

    Active - Recruiting

  • Uls Braga - Hosp. Braga

    Braga, 4710-243
    Portugal

    Active - Recruiting

  • Champalimaud Foundation Champalimaud Centre

    Lisbon, 1400-038
    Portugal

    Active - Recruiting

  • Instituto Portugues de Oncologia

    Porto, 4200 072
    Portugal

    Active - Recruiting

  • Uls Hosp Sao Joao

    Porto, 4200 319
    Portugal

    Active - Recruiting

  • Uls Hosp. Sao Joao

    Porto, 4200-319
    Portugal

    Active - Recruiting

  • Hosp. Univ. Germans Trias I Pujol

    Badalona, 08916
    Spain

    Active - Recruiting

  • Hosp Univ Vall D Hebron

    Barcelona, 08035
    Spain

    Active - Recruiting

  • Hosp. de La Santa Creu I Sant Pau

    Barcelona, 08025
    Spain

    Active - Recruiting

  • Hosp. Univ. Virgen de Las Nieves

    Granada, 18014
    Spain

    Active - Recruiting

  • Hosp. de Jerez de La Frontera

    Jerez de la Frontera, 11407
    Spain

    Active - Recruiting

  • Hosp Univ Hm Sanchinarro

    Madrid, 28050
    Spain

    Active - Recruiting

  • Hosp. Univ. 12 De Octubre

    Madrid, 28041
    Spain

    Active - Recruiting

  • Hosp. Univ. 12 de Octubre

    Madrid, 28041
    Spain

    Active - Recruiting

  • Hosp. Univ. Hm Sanchinarro

    Madrid, 28050
    Spain

    Active - Recruiting

  • Hosp. Univ. La Paz

    Madrid, 28046
    Spain

    Active - Recruiting

  • Hosp. Univ. Son Espases

    Palma de Mallorca, 07120
    Spain

    Active - Recruiting

  • Hosp. Quiron Madrid Pozuelo

    Pozuelo de Alarcon, 28223
    Spain

    Active - Recruiting

  • Hosp Clinico Univ de Salamanca

    Salamanca, 37007
    Spain

    Active - Recruiting

  • Hosp. Clinico Univ. de Salamanca

    Salamanca, 37007
    Spain

    Active - Recruiting

  • Hosp. Mutua Terrassa

    Terrassa, 08221
    Spain

    Active - Recruiting

  • Hosp. Clinico Univ. de Valencia

    Valencia, 46010
    Spain

    Active - Recruiting

  • Falu Lasarett

    Falun, 791 82
    Sweden

    Active - Recruiting

  • Sahlgrenska University Hospital

    Gothenburg, 413 45
    Sweden

    Site Not Available

  • Skanes universitetssjukhus

    Lund, 221 85
    Sweden

    Active - Recruiting

  • Karolinska University Hospital Huddinge

    Stockholm, 141 86
    Sweden

    Active - Recruiting

  • Karolinska University Hospital, Huddinge

    Stockholm, 141 86
    Sweden

    Active - Recruiting

  • Universitetssjukhuset Orebro

    Örebro, 701 85
    Sweden

    Active - Recruiting

  • Universitatsspital Basel

    Basel, 4031
    Switzerland

    Site Not Available

  • INSELSPITAL, Universitätsspital Bern

    Bern, 3010
    Switzerland

    Active - Recruiting

  • Inselspital Universitatsspital Bern

    Bern, 3010
    Switzerland

    Active - Recruiting

  • Kantonsspital St Gallen

    St. Gallen, 9007
    Switzerland

    Active - Recruiting

  • Kantonsspital St.Gallen

    St. Gallen, 9007
    Switzerland

    Active - Recruiting

  • UniversitaetsSpital Zuerich

    Zürich, 8091
    Switzerland

    Site Not Available

  • Ankara University Medical Faculty

    Ankara, 06590
    Turkey

    Active - Recruiting

  • Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital

    Ankara, 06200
    Turkey

    Active - Recruiting

  • Liv Hospital Ankara

    Ankara, 06680
    Turkey

    Active - Recruiting

  • Memorial Antalya Hospital

    Antalya, 07025
    Turkey

    Active - Recruiting

  • Pamukkale University Medical Faculty

    Denizli, 20160
    Turkey

    Completed

  • Istanbul University Istanbul Medical Faculty

    Istanbul, 34093
    Turkey

    Site Not Available

  • Medipol University Hospital

    Istanbul, 34214
    Turkey

    Active - Recruiting

  • Dokuz Eylul University Medical Faculty

    Izmir, 35340
    Turkey

    Completed

  • Ondokuz Mayis University

    Samsun, 55280
    Turkey

    Active - Recruiting

  • Blackpool Victoria Hospital

    Blackpool, FY3 8NR
    United Kingdom

    Active - Recruiting

  • University Hospitals Bristol and Weston

    Bristol, BS1 3NU
    United Kingdom

    Active - Recruiting

  • Addenbrooke's Hospital

    Cambridge, CB2 0QQ
    United Kingdom

    Active - Recruiting

  • Kent and Canterbury Hospital

    Canterbury, CT1 3NG
    United Kingdom

    Active - Recruiting

  • Western General Hospital

    Edinburgh, EH4 2XU
    United Kingdom

    Active - Recruiting

  • St James University Hospital

    Leeds, LS9 7TF
    United Kingdom

    Site Not Available

  • Imperial College Healthcare

    London, W2 1NY
    United Kingdom

    Active - Recruiting

  • University College London Hospitals

    London, NW1 2BU
    United Kingdom

    Active - Recruiting

  • New Cross Hospital

    Wolverhampton, WV10 0QP
    United Kingdom

    Active - Recruiting

  • University of Arizona Cancer Center

    Tucson, Arizona 85719
    United States

    Site Not Available

  • City of Hope Cancer Center

    Duarte, California 91010
    United States

    Active - Recruiting

  • City of Hope Orange County Lennar Foundation Cancer Center

    Irvine, California 92618
    United States

    Active - Recruiting

  • University of California San Diego (UCSD) - The Rebecca and John Moores Cancer Center

    La Jolla, California 92037
    United States

    Site Not Available

  • University of Connecticut

    Farmington, Connecticut 06030
    United States

    Site Not Available

  • MedStar Georgetown University Hospital

    Washington, District of Columbia 20007
    United States

    Site Not Available

  • Cleveland Clinic Florida - Oncology

    Weston, Florida 33331
    United States

    Site Not Available

  • Georgia Cancer Center

    Augusta, Georgia 30912
    United States

    Site Not Available

  • Mission Cancer Blood

    Des Moines, Iowa 50309
    United States

    Site Not Available

  • University of Iowa Health Care

    Waukee, Iowa 50263
    United States

    Active - Recruiting

  • Norton Cancer Institute

    Louisville, Kentucky 40207
    United States

    Active - Recruiting

  • LSUHSC Shreveport Feist-Weiller Cancer Center

    Shreveport, Louisiana 71103
    United States

    Site Not Available

  • Tufts Medical Center

    Boston, Massachusetts 02111
    United States

    Site Not Available

  • Henry Ford Hospital - Hematology/oncology

    Detroit, Michigan 48202
    United States

    Site Not Available

  • Cancer And Hematology Centers of Western Michigan PC

    Grand Rapids, Michigan 49503
    United States

    Active - Recruiting

  • Providence Cancer Center

    Southfield, Michigan 48075
    United States

    Site Not Available

  • Washington University School of Medicine

    Saint Louis, Missouri 63110
    United States

    Site Not Available

  • University of Nebraska Medical Center

    Omaha, Nebraska 68198 0600
    United States

    Active - Recruiting

  • Cooper Health System MD Anderson Cancer Center at Cooper

    Camden, New Jersey 08103
    United States

    Site Not Available

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey 08901
    United States

    Site Not Available

  • Christus St. Vincent Regional Cancer Center

    Santa Fe, New Mexico 87505
    United States

    Active - Recruiting

  • Weill Cornell Medical College

    New York, New York 10065
    United States

    Site Not Available

  • Stony Brook University Medical Center

    Stony Brook, New York 11794
    United States

    Site Not Available

  • Levine Cancer Institute

    Charlotte, North Carolina 28204
    United States

    Site Not Available

  • Duke University Medical Center

    Durham, North Carolina 27705
    United States

    Site Not Available

  • Durham VAMC

    Durham, North Carolina 27705
    United States

    Active - Recruiting

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio 44106
    United States

    Site Not Available

  • Oregon Health & Science University

    Portland, Oregon 97239
    United States

    Site Not Available

  • Lehigh Valley Health Network

    Allentown, Pennsylvania 18103
    United States

    Site Not Available

  • University of Texas Southwestern Medical Center

    Dallas, Texas 75390
    United States

    Site Not Available

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas 77030
    United States

    Site Not Available

  • Fort Belvoir Community Hospital

    Fort Belvoir, Virginia 22060
    United States

    Site Not Available

  • Seattle Cancer Care Alliance

    Seattle, Washington 98109
    United States

    Site Not Available

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