CERENOVUS Neurothrombectomy Devices Registry

Inclusion Criteria:

1. Age ≥ 18
2. The participant or the participant's legally authorized representative has signed anddated an Informed Consent Form. In the event that local regulations allow foralternative approaches of consent, these must be fulfilled as approved by the sponsorand site's ethics committee/regulatory authority (if applicable)
3. Participants experiencing acute ischemic stroke with angiographic confirmation ofLarge Vessel Occlusion (LVO)
4. A clinical decision has been made to use a CERENOVUS neurothrombectomy device (EmboTrap® Revascularization Device and/or Large Bore Catheter/EMBOVAC AspirationCatheter) independently and prior to enrollment in the research study
5. A CERENOVUS neurothrombectomy device is the first attempted primary device/techniquefor mechanical thrombectomy for the intracranial occlusion in the participant. Thefollowing primary devices/techniques are eligible for this study: a) EmboTrap®Revascularization Device alone b) EmboTrap® Revascularization Device + co-aspirationwith the Large Bore Catheter/EMBOVAC Aspiration Catheter c) EmboTrap®Revascularization Device + co-aspiration with any other aspiration catheter d) LargeBore Catheter/EMBOVAC Aspiration Catheter alone (that is, direct aspiration with nostent retriever in the first attempted technique)

Exclusion Criteria:

1. Currently participating in an investigational (drug, device, etc) clinical trial thatmay confound study endpoints. Patients in observational, natural history, and/orepidemiological studies not involving intervention are eligible
2. Confirmation of positive pregnancy test according to site specific standard of care (example, test, verbal communication)