Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Attentional Control: an fMRI Study on Healthy Participants

Last updated: November 14, 2022
Sponsor: University of Tehran
Overall Status: Active - Recruiting

Phase

N/A

Condition

Healthy Volunteers

Treatment

N/A

Clinical Study ID

NCT05613790
511098020
  • Ages 20-39
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

In a randomized, triple-blind, sham-controlled clinical trial, we will assess the effect of a single session frontal cortex High-Definition transcranial Direct Current Stimulation (HD-tDCS) on brain activity and functional connectivity underlying the behavioral change in attentional control in healthy participants. Participants will be recruited after meeting the inclusion criteria and will be randomly assigned to active or sham stimulation groups. All participants will undergo resting-state functional Magnetic Resonance Imaging (rsfMRI) scan and perform an Attention Network Test (ANT) in a functional Magnetic Resonance Imaging (fMRI) scanner before and after receiving a single session of active or sham HD-tDCS.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Right-handed healthy adults
  • Age range 20-39 years
  • Normal or corrected-to-normal vision
  • Willing and capable of following study protocol requirements given in the informedconsent

Exclusion

Exclusion Criteria:

  • Psychiatric conditions (e.g., depression and generalized anxiety disorder, etc.)
  • Medical illness or neurological disorder (e.g., cardiovascular illness, anemia,respiratory illness, neurological illness, seizure, etc.)
  • Current abuse of drugs or alcohol
  • Any conditions that prevent undergoing an fMRI scan or tDCS stimulation according tothe fMRI and tDCS safety checklists

Study Design

Total Participants: 24
Study Start date:
November 02, 2022
Estimated Completion Date:
March 31, 2023

Connect with a study center

  • Faculty of Psychology

    Tehran, 1445983861
    Iran, Islamic Republic of

    Active - Recruiting

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