Colonisation Efficacy of a Probiotic Chewing Gum.

Last updated: November 21, 2022
Sponsor: BLIS Technologies Limited
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05624177
BLTCT2022/7
  • Ages 18-80
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

To evaluate the colonization efficacy (the ability of a probiotic bacteria to remain in the mouth) delivered in a chewing gum format. The chewing gum contains Streptococcus salivarius probiotic and the study is to be done in health adults.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • In general, good health
  • Practice good oral hygiene

Exclusion

Exclusion Criteria:

  • Have a history of autoimmune disease or are immune compromised.
  • Are on concurrent antibiotic therapy, or regular antibiotic use within last one week
  • People with allergies or sensitivities to dairy.

Study Design

Total Participants: 20
Study Start date:
December 01, 2022
Estimated Completion Date:
March 31, 2023

Study Description

This is a single blind, randomized controlled study to evaluate the colonization effectiveness of a chewing gum containing a commercially available probiotic bacterium. Participants will be randomly assigned to one of the two groups consuming chewing gum containing Streptococcus salivarius M18 over a 7-day period. Saliva samples will be collected at pre determined points (pre and post intervention). Colonization efficacy will be determined by enumerating the probiotic from the saliva samples using standard microbiological techniques.

Connect with a study center

  • Blis Technologies Ltd

    Dunedin, Otago 9012
    New Zealand

    Active - Recruiting

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