Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis

Last updated: March 27, 2023
Sponsor: Far Eastern Memorial Hospital
Overall Status: Active - Recruiting

Phase

3

Condition

Endometriosis

Treatment

N/A

Clinical Study ID

NCT05697471
111207-F
  • Ages > 20
  • Female

Study Summary

The aim of this study is to evaluate the efficacy between dienogest and danazol.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • > 20 years old
  • Have an endometriosis-related condition (including adenomyosis, adenomyoma, ovarianendometrioma, or pelvic endometriosis).

Exclusion

Exclusion Criteria:

  • Minors.
  • Have a history of breast cancer or other cancers.
  • Patients with vascular obstruction such as stroke.

Study Design

Total Participants: 120
Study Start date:
February 25, 2023
Estimated Completion Date:
December 31, 2025

Study Description

Objective: Women with adenomyosis or endometripsis are often suffered from dysmenorrhea or menorrhagia. Dienogest and danazol are frequently used for the treatment of endometriosis. However, there was no literature mentioned about which medication is better for the treatment of endometriosis. Thus, the aim of this study is to evaluate the efficacy between dienogest and danazol.

Methods: All consecutive women, who have endometriosis, will be randomized to receive dienogest or danazol treatment, and will assess symptoms severity, receive CA125 examination, sonographic examination at baseline, 4 weeks and 16 weeks after treatment.

Connect with a study center

  • Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital

    Banqiao, New Taipei 22050
    Taiwan

    Active - Recruiting

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