Effects of Recruitment Manouever on Oxygenation, Oxygen Reserve Index and Postoperative Pulmonary Complications

Last updated: January 27, 2023
Sponsor: Balikesir University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Diabetes Prevention

Obesity

Treatment

N/A

Clinical Study ID

NCT05705245
2021/138
  • Ages 18-65
  • All Genders

Study Summary

General anesthesia and mechanical ventilation decrease pulmonar volume; attenuate small airway closure, atelectasis, and increase the rate of hypoxia and postoperative pulmonary complications. Lung volume in obese patients decreases inversely with the increase in body mass index. Obesity is associated with increased atelectasis, hypoxia and postoperative pulmonary complication rates during anesthesia . Alveolar recruitment maneuver is a technique where high positive end-expiratory pressure (PEEP) is applied for for short periods, follwed by a continuous PEEP appşication throughout surgery. This has become a standard practice during anesthesia in recent years. Oxygen reserve index (ORi) is an index measured with a non-invasive finger-tip sensor and shows the oxygen content of the venous blood. It is effective at high oxygen levels and may indicate the presence of hyperoxia. Our aim is to examine the effect of alveolar recruitment maneuver on oxygenation parameters under anesthesia and the correlation with ORi in morbidly obese patients.

Eligibility Criteria

Inclusion

Inclusion Criteria: Bariatric surgery general anesthesia and mechanical ventilation via orotracheal entubationAge between 18-65 ASA I-III BMI > 40 m-2

Exclusion

Exclusion Criteria: Previous history of thorasic surgery, pneumothorax Chemo or Radiotherapy to the chestwithin 2 months History of Respiratory disease (COPD, emphysema, pneumonia, lungmalignancy, Lung Bulla ) Emergency surgery Cardiovascular, renal, hepatic, neuromusculardisease İntracrabial pathology or trauma High intraoptic pressure Pulmonary HypertensionPregnancy Criticall illness, or history of mechanical ventilation within 1 month

Study Design

Total Participants: 80
Study Start date:
January 22, 2022
Estimated Completion Date:
July 01, 2024

Study Description

Patients with body mass index> 40 m2, scheduled for bariatric surgery under general anesthesia will be monitorised with the ORi sensor and monitored at regular intervals. Preoperative and postoperative lung aeration will be evaluated with lung ultrasaund. İntraoperative standart anesthesia will be administered by an anesthesiolıgist not aware of the ultrasound. Alveolar recruitment will be applied by the same anesthesiologist if necessary. Blood gas samples obtained throughout surgery will be evaluated. ORİ values and intraoperative vital, respiratory, neuromuscular monitoring parameters will be obtained. Postoperative pulmonary complicationsa will be evaluated at postoperative day 5.

Finding will be compared between patients who received recruitment and who did not.

Connect with a study center

  • Balikesir University Hospital

    Balikesir, 10145
    Turkey

    Active - Recruiting

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