Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals With Temporomandibular Dysfunction

Last updated: July 15, 2025
Sponsor: Karadeniz Technical University
Overall Status: Completed

Phase

N/A

Condition

Pain

Oral Facial Pain

Treatment

N/A

Clinical Study ID

NCT05993494
KTU-FTR-2023/6
  • Ages 18-65
  • All Genders

Study Summary

Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Recent research has focused specifically on pain catastrophe, kinesiophobia, and central sensitization in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Between the ages of 18-65,

  • Having complaints related to TMJ for at least 3 months,

  • Patients diagnosed with TMD as a result of clinical and radiological evaluation bythe dentist

Exclusion

Exclusion Criteria:

  • Cognitive problems,

  • Any systemic joint or muscle disease (e.g. fibromyalgia, rheumatoid arthritis),

  • Serious systemic diseases,

  • Any neurological disorder (e.g. trigeminal neuralgia),

  • Pregnancy, breastfeeding status,

  • Previous treatment for TMJ or orofacial muscle pain

Study Design

Total Participants: 90
Study Start date:
May 15, 2023
Estimated Completion Date:
May 30, 2025

Study Description

Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Psychological factors are stated as comorbid in individuals with TMD. Individuals with TMD-related pain show higher levels of stress, anxiety, depression, somatic awareness, pain catastrophizing, and kinesiophobia compared to controls. Therefore, recent research has focused on pain catastrophe, kinesiophobia, and central sensitization, especially in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction. Ninety patients aged 18-65 years, who have TME-related complaints for at least 3 months, and diagnosed with TMD as a result of clinical and radiological evaluation by a dentist will be included in the study.

Connect with a study center

  • Karadeniz Technical University

    Trabzon, 61000
    Turkey

    Site Not Available

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