Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation

Inclusion Criteria:

• Age over 18 years
• Written informed consent
• Diagnosis of recurrent or isolated depressive episode according to DSM IV criteria (A.P.A. 1994).
• Stable antidepressant treatment for 3 weeks
• MADRS score ≥ 20
• SSI score > 3
• Subject affiliated to a health insurance system
• Woman with effective contraception and agreeing to maintain it throughout the studyperiod.

Exclusion Criteria:

• Depression with psychotic features Axis I (DSM IV) co-morbid diagnosis ofschizophrenia, alcohol and/or other substance dependence (or abuse) (lifetime)
• Patient who has already undergone an electroconvulsive therapy course for the currentepisode and does not respond to this treatment
• Patient deprived of liberty
• Patient with high suicide risk (item 10 MADRS > 4) in the absence of hospitalization
• Contraindication to tDCS: intracerebral metallic implant (with the exception of dentalimplants), cardiac pacemaker, active or non-implanted devices in the region of thehead, acute eczema in the planned stimulation area
• Pregnant, parturient or breastfeeding woman
• Simultaneous participation in another interventional research