A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

Inclusion Criteria:

1. Patients who completed treatment in the parent trials (1305-0014 or 1305-0023)without prematurely discontinuing treatment permanently according to protocol (i.e.completed treatment with or without temporary treatment interruption)

2. Signed and dated written informed consent in accordance with ICH-GCP and locallegislation prior to admission to the trial

3. Women of childbearing potential (WOCBP) must be ready and able to use highlyeffective methods of birth control per ICH M3 (R2) that result in a low failure rateof less than 1% per year when used consistently and correctly. WOCBP taking oralcontraceptives (OCs) also have to ensure the use of one barrier method during sexualintercourse with their partner, e.g., condom to account for the risk of potentiallyreduced efficacy of the OCs in the event of severe vomiting and diarrhoea. ForFrance, fertile males must be ready and able to use acceptable methods of birthcontrol

Exclusion Criteria:

1. Any disease that may put the patient at risk when participating in this trial atinvestigator's discretion.

2. Patient exhibits suicidality, in the clinical judgment of the investigator oraccording to the following criteria at Visit 1:

• any suicidal behaviour (i.e. actual attempt, interrupted attempt, abortedattempt, or preparatory acts or behaviour)

• any suicidal ideation of type 4 or 5 in the Columbia-Suicide Severity RatingScale (C-SSRS) (i.e. active suicidal thought with intent but without specificplan, or active suicidal thought with plan and intent)

3. Patients with clinically relevant severe depression at investigator's discretion ora Hospital Anxiety and Depression Scale (HADS) subscore >14 at Visit 1.

4. An occurrence of malignant neoplasm other than appropriately treated basal cellcarcinoma or in situ squamous cell carcinoma of the skin or in situ carcinoma ofuterine cervix at Visit 1.

5. Patient will undergo lung transplantation, with an assigned date of surgery.

6. Patients with a Body Mass index (BMI) <18.5 kg/m² that experienced an additional,unexplained and clinically significant (>10%) weight loss during the parent trial

7. At Visit 1, patients with ongoing Adverse Event of Special Interest (AESI), exceptfor latent tuberculosis (suspected vasculitis, Drug Induced Liver Injury (DILI),severe infections) that led to temporary treatment interruption in the parent trial

8. Patients who must or wish to take restricted medications or any drug consideredlikely to interfere with the safe conduct of the trial.

Further exclusion criteria apply.