Phase
Condition
Cervical Cancer
Uterine Disorders
Treatment
Gemcitabine injection
GT101 injection
Clinical Study ID
Ages 18-70 Female
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- The Patients (or legally authorized representative) Patients (or legallyauthorized representative) must have the ability to understand the requirementsof the study, have provided written informed consent as evidenced by signatureon an informed consent form (ICF) approved by an Institutional ReviewBoard/Independent Ethics Committee (IRB/IEC) ,must have the ability tounderstand the requirements of the study);
- The patient must be 18 to 70 years of age at the time of consent;
- Must have a confirmed diagnosis of malignancy of their receptive histologies orcytology: unresectable recurrent or metastatic cervical carcinomas andpreviously received≥ 1 prior systemic therapy;
- Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1;
- Expected survival time of ≥ 12 weeks;
- Adequate normal organ and marrow function;
- Before tumor resection, the confirmatory imaging of disease progress since lasttreatment should be documented.
- 8.Patients must have measurable disease measured by Response Evaluation Criteria inSolid Tumors (RECIST) 1.1 criteria (in addition to the resected lesion).
Exclusion
Exclusion Criteria:
1.Patients with uncontrollable tumor-related pain as judged by the investigator;participants requiring painkiller must already have had a stable pain managementoptions at the time of study entry; symptomatic lesions suitable for palliativeradiotherapy should be completed prior to study entry;
2.Patients who have psychiatric disorders, alcohol, drug or substance abuse;
3.Women who are pregnant or breastfeeding, or planning to become pregnant within 1year after cell infusion;
4.Participate in other clinical trials within 4 weeks prior to screening, orplanning to participate in this study and other clinical trials at the same time;
5.Any other conditions that would make the patient unsuitable candidate for thestudy at the discretion of the investigator.
Study Design
Connect with a study center
The Fifth Medical Center of the General Hospital of the People's Liberation Army of China
Beijing, Beijing 222002
ChinaActive - Recruiting
Fujian Cancer Hospital
Fuzhou, Fujian 350014
ChinaActive - Recruiting
Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital
Shenzhen, Guangdong 518172
ChinaActive - Recruiting
Guangxi Medical University Affiliated Cancer Hospital
Guilin, Guangxi 530021
ChinaActive - Recruiting
Harbin Medical University Affiliated Cancer Hospital
Ha'erbin, Heilongjjiang 150081
ChinaActive - Recruiting
The First Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan 450052
ChinaActive - Recruiting
Henan Cancer Hospital
Zhengzhou, Henan 450003
ChinaActive - Recruiting
Hubei Cancer Hospital
Wuhan, Hubei 430079
ChinaActive - Recruiting
Xiangya Second Hospital of Central South University
Changsha, Hunan 410012
ChinaActive - Recruiting
Southeast University Affiliated Zhongda Hospital
Nanjing, Jiangsu 210009
ChinaActive - Recruiting
Jiangxi Maternal and Child Health Hospital
Nanchang, Jiangxi 330006
ChinaActive - Recruiting
Affiliated Zhongshan Hospital Dalian University
Dalian, Liaoning 116001
ChinaActive - Recruiting
Dalian Medical University First Affiliated Hospital
Dalian, Liaoning 116001
ChinaActive - Recruiting
Shandong First Medical University Affiliated Cancer Hospital
Jinan, Shandong 250117
ChinaActive - Recruiting
Jining First People's Hospital
Jining, Shandong 272002
ChinaActive - Recruiting
Fudan University Affiliated Obstetrics and Gynecology Hospital
Shanghai, Shanghai 214432
ChinaActive - Recruiting
Fudan University Shanghai Cancer Center
Shanghai, Shanghai 200032
ChinaActive - Recruiting
Shanxi Cancer Hospital
Taiyuan, Shanxi 030013
ChinaActive - Recruiting
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shanxi 710061
ChinaActive - Recruiting
Sichuan University West China Second Hospital
Chengdu, Sichuan 610044
ChinaActive - Recruiting
Yibin Second People's Hospital
Yibin, Sichuan 644002
ChinaActive - Recruiting
Tianjin Cancer Hospital
Tianjin, Tianjin 300181
ChinaActive - Recruiting
Yun Cancer Hospital
Kunming, Yunnan 650118
ChinaActive - Recruiting
Zhejiang Cancer Hospital
Hangzhou, Zhejiang 310005
ChinaActive - Recruiting
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