RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age

Last updated: March 7, 2024
Sponsor: Meyer Children's Hospital IRCCS
Overall Status: Active - Recruiting

Phase

N/A

Condition

Uveitis

Treatment

N/A

Clinical Study ID

NCT06273748
RChildUV
  • Ages 1-16
  • All Genders

Study Summary

Uveitis is an inflammatory disease of the uvea, one of the highly vascularized fundamental structures of the eye. It is a rare condition in children, with an incidence in the pediatric population ranging from 2% to 14% of all uveitis cases. The diagnosis and management of patients with uveitis rely on a multidisciplinary approach involving an ophthalmologist, a rheumatologist, and an infectious disease specialist to establish the correct diagnosis and assess the involvement of other organs. In Italy, there is no national or regional registry for non-infectious chronic uveitis as per the Prime Ministerial Decree (DPCM) of March 3, 2017 (Identification of surveillance systems and registries for mortality, tumors, and other diseases). However, many clinical centers adopt data recording systems to evaluate the quality of care and to study diseases and outcomes. The Universitary Hospital Meyer Institute Research Hospital (IRCCS) is a national referral center for managing these pediatric cases of non-infectious chronic uveitis, estimated to constitute 95% of all pediatric uveitis cases

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • diagnosis of non-infectious chronic uveitis before the age of 16;
  • signed informed consent form.

Exclusion

Exclusion Criteria:

  • Patients with a diagnosis of infectious uveitis
  • history of malignant pathology,
  • history of demyelinating pathology,
  • history of cerebral vasculitis

Study Design

Total Participants: 290
Study Start date:
February 10, 2022
Estimated Completion Date:
May 02, 2032

Connect with a study center

  • - ATTIKON General Hospital

    Athens, 12462
    Greece

    Active - Recruiting

  • Meyer Children's Hospital IRCCS

    Florence, Firenze
    Italy

    Active - Recruiting

  • Ospedale Spedali Civili di Brescia

    Brescia,
    Italy

    Site Not Available

  • IRCCS materno infantile Burlo Garofolo

    Trieste,
    Italy

    Active - Recruiting

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio 45207
    United States

    Active - Recruiting

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