A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis

Last updated: March 20, 2025
Sponsor: Sanofi
Overall Status: Active - Recruiting

Phase

2

Condition

Bronchiectasis

Treatment

Placebo

Itepekimab (SAR440340)

Clinical Study ID

NCT06280391
ACT18018
U1111-1295-3237
2023-508663-70
  • Ages 18-85
  • All Genders

Study Summary

ACT18018 is a multinational, randomized, double-blind, placebo-controlled, parallel-group, Phase 2 study with 3 treatment groups. The purpose of this study is to evaluate efficacy, safety and tolerability with 2 dosing regimens of itepekimab compared with placebo in male and/or female participants with NCFB aged 18 years of age up to 85 years of age (inclusive).

Study details include:

  • The study duration (screening, 24-52-week treatment, 20-week safety follow-up) will be up to 47-77 weeks.

  • The treatment duration will be up to 24-52 weeks.

  • The follow-up duration will be 20 weeks.

  • Site/phone visits are at a monthly interval.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participant must be 18 to 85 years of age inclusive.

  • Clinical history consistent with NCFB (cough, chronic sputum production and/orrecurrent respiratory infections).

  • Participants with a FEV1 % predicted ≥30%.

  • Participants with at least 2 moderate or 1 severe Pulmonary exacerbations (PEs) inthe past 12 months.

Exclusion

Exclusion Criteria:

Participants are excluded from the study if any of the following criteria apply:

  • Have bronchiectasis due to CF, hypogammaglobulinemia, common variableimmunodeficiency, known active nontuberculous mycobacteria (NTM) lung infection, orpulmonary fibrosis.

  • Known or suspected immunodeficiency disorder.

  • Pulmonary exacerbation which has not resolved clinically during screening period.

  • Have significant haemoptysis.

  • Have any clinically significant abnormal laboratory values at Screening or diseasesor disorders.

  • History of lung transplantation.

  • History of malignancy within 5 years before Screening, or during the screeningperiod

  • Currently being treated with antimicrobial therapy for tuberculosis (TB).

  • Currently on active treatment for allergic bronchopulmonary aspergillosis (ABPA).

  • Participants with active autoimmune disease or participants using immunosuppressivetherapy for autoimmune disease

  • Known allergy to itepekimab or to excipients

  • Live-attenuated vaccine(s) within 4 weeks prior to Screening or plans to receivesuch vaccines during the study

  • Unstable ischemic heart disease

  • Cardiomyopathy or other relevant cardiovascular disorder

  • Clinically significant new abnormal electrocardiogram (ECG) within 6 months priorto, or at Screening

  • History of human immunodeficiency virus (HIV) infection or positive HIV 1/2 serologyat Screening.

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Study Design

Total Participants: 300
Treatment Group(s): 2
Primary Treatment: Placebo
Phase: 2
Study Start date:
February 20, 2024
Estimated Completion Date:
August 11, 2026

Connect with a study center

  • Investigational Site Number : 0320004

    Caba, Buenos Aires 1427
    Argentina

    Site Not Available

  • Investigational Site Number : 0320002

    La Plata, Buenos Aires 1900
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320001

    Buenos Aires, 1414
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320003

    Buenos Aires, 1121
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320004

    Buenos Aires, 1430
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320008

    Buenos Aires, 1280
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320001

    Ciudad Autonoma Buenos Aires, C1414AIF
    Argentina

    Site Not Available

  • Investigational Site Number : 0320007

    Córdoba, 5003
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320006

    Mendoza, 5500
    Argentina

    Active - Recruiting

  • Investigational Site Number : 0320005

    San Miguel de Tucuman, T4000IAI
    Argentina

    Site Not Available

  • Investigational Site Number : 0320005

    San Miguel de Tucumán, 4000
    Argentina

    Active - Recruiting

  • OC ONCOCLINICAS UMC- Site Number : 0760007

    Uberlandia, Minas Gerais 38411-186
    Brazil

    Active - Recruiting

  • Hospital São Lucas da PUCRS - Porto Alegre - Avenida Ipiranga- Site Number : 0760001

    Porto Alegre, Rio Grande Do Sul 90610-000
    Brazil

    Site Not Available

  • Irmandade da Santa Casa de Misericordia de Porto Alegre- Site Number : 0760005

    Porto Alegre, Rio Grande Do Sul 90020-090
    Brazil

    Active - Recruiting

  • Irmandade da Santa Casa de Misericórdia de Porto Alegre- Site Number : 0760005

    Porto Alegre, Rio Grande Do Sul 90020-090
    Brazil

    Active - Recruiting

  • WM Clinica Pneumologica- Site Number : 0760004

    Porto Alegre, Rio Grande Do Sul 91010-004
    Brazil

    Site Not Available

  • InCor - Instituto do Coraçao do Hospital das Clinicas da FMUSP Site Number : 0760002

    Sao Paulo, São Paulo 05403-900
    Brazil

    Site Not Available

  • Incor - Instituto do Coracao- Site Number : 0760002

    São Paulo, 05403-900
    Brazil

    Site Not Available

  • Investigational Site Number : 1240003

    Guelph, Ontario N1H 6J2
    Canada

    Site Not Available

  • Investigational Site Number : 1240005

    Sherbrooke, Quebec J1H 5N4
    Canada

    Site Not Available

  • Investigational Site Number : 1240001

    Trois-Rivieres, Quebec G8T 7A1
    Canada

    Site Not Available

  • Investigational Site Number : 1240001

    Trois-rivières, Quebec G8T 7A1
    Canada

    Site Not Available

  • Investigational Site Number : 1520001

    Talca, Maule 3465584
    Chile

    Site Not Available

  • Investigational Site Number : 1520002

    Santiago, Reg Metropolitana De Santiago 7500692
    Chile

    Site Not Available

  • Investigational Site Number : 1520003

    Santiago, Reg Metropolitana De Santiago 7500587
    Chile

    Site Not Available

  • Investigational Site Number : 1520004

    Quillota, Valparaíso 2260877
    Chile

    Site Not Available

  • Investigational Site Number : 1560005

    Beijing, 100020
    China

    Completed

  • Investigational Site Number : 1560008

    Changchun, 130021
    China

    Site Not Available

  • Investigational Site Number : 1560004

    Chengdu, 610041
    China

    Site Not Available

  • Investigational Site Number : 1560001

    Guangzhou, 510120
    China

    Site Not Available

  • Investigational Site Number : 1560002

    Shanghai, 200433
    China

    Active - Recruiting

  • Investigational Site Number : 1560006

    Shanghai, 200025
    China

    Active - Recruiting

  • Investigational Site Number : 1560007

    Shenyang, 110004
    China

    Site Not Available

  • Investigational Site Number : 1560003

    Xuzhou, 221006
    China

    Site Not Available

  • Investigational Site Number : 2030006

    Cesky Krumlov, 381 01
    Czechia

    Site Not Available

  • Investigational Site Number : 2030002

    Jindrichuv Hradec III, 37701
    Czechia

    Site Not Available

  • Investigational Site Number : 2030002

    Jindřichův Hradec, 377 01
    Czechia

    Active - Recruiting

  • Investigational Site Number : 2030004

    Kralupy Nad Vltavou, 278 01
    Czechia

    Active - Recruiting

  • Investigational Site Number : 2030003

    Pilsen, 305 99
    Czechia

    Active - Recruiting

  • Investigational Site Number : 2030005

    Prague, 190 00
    Czechia

    Active - Recruiting

  • Investigational Site Number : 2030005

    Praha 9, 190 00
    Czechia

    Site Not Available

  • Investigational Site Number : 2030006

    Český Krumlov, 381 01
    Czechia

    Active - Recruiting

  • Investigational Site Number : 2080002

    Aalborg, 9000
    Denmark

    Site Not Available

  • Investigational Site Number : 2080005

    Aarhus, 8200
    Denmark

    Site Not Available

  • Investigational Site Number : 2080005

    Aarhus N, 8200
    Denmark

    Site Not Available

  • Investigational Site Number : 2080004

    Odense, 5000
    Denmark

    Site Not Available

  • Investigational Site Number : 2080004

    Odense C, 5000
    Denmark

    Site Not Available

  • Investigational Site Number : 2080001

    Vejle, 7100
    Denmark

    Site Not Available

  • Investigational Site Number : 2500005

    Brest, 29200
    France

    Active - Recruiting

  • Investigational Site Number : 2500005

    Brest cedex 2, 29609
    France

    Site Not Available

  • Investigational Site Number : 2500001

    Lyon, 69004
    France

    Active - Recruiting

  • Investigational Site Number : 2500002

    Montpellier, 34090
    France

    Active - Recruiting

  • Investigational Site Number : 2500004

    Nice, 06001
    France

    Active - Recruiting

  • Investigational Site Number : 2500003

    Paris, 75679
    France

    Active - Recruiting

  • Investigational Site Number : 2500007

    Pontoise, 95300
    France

    Active - Recruiting

  • Investigational Site Number : 2500006

    Saint-herblain, 44800
    France

    Active - Recruiting

  • Investigational Site Number : 2760001

    Ahrensburg, 22926
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760005

    Bendorf, 56170
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760010

    Berlin, 12159
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760009

    Cottbus, 03050
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760007

    Essen, 45239
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760003

    Frankfurt, 60596
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760003

    Frankfurt am Main, 60596
    Germany

    Site Not Available

  • Investigational Site Number : 2760001

    GROßHANSDORF, 22927
    Germany

    Site Not Available

  • Investigational Site Number : 2760004

    Lübeck, 23552
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760002

    Mainz, 55128
    Germany

    Active - Recruiting

  • Investigational Site Number : 2760011

    Meunchen, 80336
    Germany

    Site Not Available

  • Investigational Site Number : 2760011

    Munich, 80337
    Germany

    Active - Recruiting

  • Investigational Site Number : 3000002

    Athens, 115 27
    Greece

    Active - Recruiting

  • Investigational Site Number : 3000001

    Ioannina, 455 00
    Greece

    Site Not Available

  • Investigational Site Number : 3000003

    Thessaloniki, 570 10
    Greece

    Site Not Available

  • Investigational Site Number : 3760008

    Ashkelon, 7830604
    Israel

    Site Not Available

  • Investigational Site Number : 3760006

    Haifa, 3436212
    Israel

    Site Not Available

  • Investigational Site Number : 3760001

    Jerusalem, 9112001
    Israel

    Site Not Available

  • Investigational Site Number : 3760003

    Jerusalem, 9103102
    Israel

    Site Not Available

  • Investigational Site Number : 3760002

    Petah Tikva, 4941492
    Israel

    Site Not Available

  • Investigational Site Number : 3760002

    Petah-Tikva, 49100
    Israel

    Site Not Available

  • Investigational Site Number : 3760009

    Ramat Gan, 5262100
    Israel

    Site Not Available

  • Investigational Site Number : 3760004

    Rehovot, 7610001
    Israel

    Site Not Available

  • Investigational Site Number : 3760007

    Tel Aviv, 6423906
    Israel

    Site Not Available

  • Investigational Site Number : 3760010

    Tel Aviv, 6789140
    Israel

    Site Not Available

  • Investigational Site Number : 3760010

    Tel-Aviv,
    Israel

    Site Not Available

  • Investigational Site Number : 3800001

    Milan, Lombardia 20122
    Italy

    Active - Recruiting

  • Investigational Site Number : 3800001

    Milano, Lombardia 20122
    Italy

    Site Not Available

  • Investigational Site Number : 3800002

    Rozzano, Milano 20089
    Italy

    Active - Recruiting

  • Investigational Site Number : 3800004

    Palermo, 90127
    Italy

    Active - Recruiting

  • Investigational Site Number : 3800003

    Pavia, 27100
    Italy

    Active - Recruiting

  • Investigational Site Number : 3800006

    Reggio Emilia, 42123
    Italy

    Active - Recruiting

  • Investigational Site Number : 3920002

    Kamogawa, Chiba 296-0041
    Japan

    Site Not Available

  • Investigational Site Number : 3920002

    Kamogawa-shi, Chiba 296-0041
    Japan

    Site Not Available

  • Investigational Site Number : 3920004

    Himeji, Hyogo 670-0849
    Japan

    Site Not Available

  • Investigational Site Number : 3920004

    Himeji-shi, Hyogo 670-0849
    Japan

    Site Not Available

  • Investigational Site Number : 3920005

    Kiyose, Tokyo 204-8522
    Japan

    Site Not Available

  • Investigational Site Number : 3920005

    Kiyose-City, Tokyo 204-8522
    Japan

    Site Not Available

  • Investigational Site Number : 3920001

    Shinagawa-ku, Tokyo 140-8522
    Japan

    Site Not Available

  • Investigational Site Number : 3920003

    Shinjuku-ku, Tokyo 162-8655
    Japan

    Site Not Available

  • Investigational Site Number : 3920001

    Tokyo, 140-8522
    Japan

    Site Not Available

  • Investigational Site Number : 3920003

    Tokyo, 162-8655
    Japan

    Site Not Available

  • Investigational Site Number : 5280002

    Alkmaar, 1815 JD
    Netherlands

    Site Not Available

  • Investigational Site Number : 5280005

    Amsterdam, 1105 AZ
    Netherlands

    Site Not Available

  • Investigational Site Number : 5280004

    Breda, 4818 CK
    Netherlands

    Site Not Available

  • Investigational Site Number : 5280003

    Den Haag, 2545 AA
    Netherlands

    Site Not Available

  • Investigational Site Number : 5280001

    Rotterdam, 3015 CE
    Netherlands

    Site Not Available

  • Investigational Site Number : 5280003

    The Hague, 2545 CH
    Netherlands

    Site Not Available

  • Investigational Site Number : 6160005

    Lodz, Lódzkie 90-153
    Poland

    Active - Recruiting

  • Investigational Site Number : 6160001

    Bialystok, Podlaskie 15-044
    Poland

    Active - Recruiting

  • Investigational Site Number : 6160002

    Ostrowiec Swietokrzyski, Swietokrzyskie 27-400
    Poland

    Active - Recruiting

  • Investigational Site Number : 6160003

    Lodz, 90-302
    Poland

    Active - Recruiting

  • Investigational Site Number : 6160006

    Wejherowo, 84-200
    Poland

    Active - Recruiting

  • Investigational Site Number : 7240003

    Barcelona, Barcelona [Barcelona] 08035
    Spain

    Site Not Available

  • Investigational Site Number : 7240006

    Barcelona, Barcelona [Barcelona] 08036
    Spain

    Site Not Available

  • Investigational Site Number : 7240007

    Barcelona, Barcelona [Barcelona] 08017
    Spain

    Site Not Available

  • Investigational Site Number : 7240001

    Hospitalet de Llobregat, Barcelona [Barcelona] 08907
    Spain

    Site Not Available

  • Investigational Site Number : 7240001

    L'hospitalet de Llobregat, Barcelona [Barcelona] 08907
    Spain

    Site Not Available

  • Investigational Site Number : 7240009

    Santander, Cantabria 39008
    Spain

    Site Not Available

  • Investigational Site Number : 7240011

    Girona, Girona [Gerona] 17007
    Spain

    Active - Recruiting

  • Investigational Site Number : 7240012

    Girona, Girona [Gerona] 17005
    Spain

    Site Not Available

  • Investigational Site Number : 7240002

    Madrid, Madrid, Comunidad De 28007
    Spain

    Site Not Available

  • Investigational Site Number : 7240002

    Madrid / Madrid, Madrid, Comunidad De 28007
    Spain

    Site Not Available

  • Investigational Site Number : 7240010

    Valencia, 46026
    Spain

    Site Not Available

  • Investigational Site Number : 1580005

    Kaohsiung, 807
    Taiwan

    Site Not Available

  • Investigational Site Number : 1580005

    Kaohsiung City, 807
    Taiwan

    Site Not Available

  • Investigational Site Number : 1580002

    New Taipei City, 220
    Taiwan

    Completed

  • Investigational Site Number : 1580006

    Taichung, 404
    Taiwan

    Site Not Available

  • Investigational Site Number : 1580003

    Taipei, 11031
    Taiwan

    Site Not Available

  • Investigational Site Number : 1580003

    Taipei City, 110
    Taiwan

    Site Not Available

  • Investigational Site Number : 1580004

    Taipei City, 100
    Taiwan

    Site Not Available

  • Investigational Site Number : 7920003

    Adana, 01330
    Turkey

    Active - Recruiting

  • Investigational Site Number : 7920002

    Akdeniz, 33070
    Turkey

    Active - Recruiting

  • Investigational Site Number : 7920005

    Ankara, 06620
    Turkey

    Active - Recruiting

  • Investigational Site Number : 7920001

    Istanbul, 34093
    Turkey

    Active - Recruiting

  • Investigational Site Number : 7920004

    Izmit, 41001
    Turkey

    Active - Recruiting

  • Investigational Site Number : 7920004

    Kocaeli, 41100
    Turkey

    Site Not Available

  • Investigational Site Number : 7920002

    Mersin, 33070
    Turkey

    Site Not Available

  • Investigational Site Number : 7920006

    Samsun, 55139
    Turkey

    Active - Recruiting

  • Investigational Site Number : 8260009

    Cambridge, Cambridgeshire CB23 3RE
    United Kingdom

    Active - Recruiting

  • Investigational Site Number : 8260008

    Norwich, Norfolk NR4 7UY
    United Kingdom

    Active - Recruiting

  • Investigational Site Number : 8260003

    North Shields, North Tyneside NE29 8NH
    United Kingdom

    Active - Recruiting

  • Investigational Site Number : 8260003

    Tyne And Wear, North Tyneside NE29 8NH
    United Kingdom

    Site Not Available

  • Investigational Site Number : 8260004

    Lancaster, LA1 4RP
    United Kingdom

    Active - Recruiting

  • Investigational Site Number : 8260001

    Newcastle Upon Tyne, NE7 7DN
    United Kingdom

    Active - Recruiting

  • Investigational Site Number : 8260005

    Reading, RG1 5AN
    United Kingdom

    Active - Recruiting

  • University of Alabama at Birmingham- Site Number : 8400040

    Birmingham, Alabama 35233
    United States

    Active - Recruiting

  • Phoenix Medical Group- Site Number : 8400033

    Peoria, Arizona 85381
    United States

    Site Not Available

  • Pulmonary Associates - Phoenix - East McDowell Road- Site Number : 8400012

    Phoenix, Arizona 85006
    United States

    Active - Recruiting

  • Pulmonary Associates Site Number : 8400012

    Phoenix, Arizona 85006
    United States

    Active - Recruiting

  • Southern California Institute For Respiratory Diseases, Inc. Site Number : 8400002

    Los Angeles, California 90048
    United States

    Active - Recruiting

  • Southern California Institute for Respiratory Diseases- Site Number : 8400002

    Los Angeles, California 90048
    United States

    Site Not Available

  • Institute Healthcare Assessment- Site Number : 8400037

    San Diego, California 92120
    United States

    Active - Recruiting

  • Institute of HealthCare Assessment, Inc. Site Number : 8400037

    San Diego, California 92120
    United States

    Active - Recruiting

  • Allianz Research Institute Site Number : 8400013

    Westminster, California 92683
    United States

    Active - Recruiting

  • Allianz Research Institute- Site Number : 8400013

    Westminster, California 92683
    United States

    Active - Recruiting

  • Allianz Research Institute CO Site Number : 8400038

    Aurora, Colorado 80014
    United States

    Active - Recruiting

  • Allianz Research Institute CO- Site Number : 8400038

    Aurora, Colorado 80014
    United States

    Active - Recruiting

  • University Of Connecticut Health Center Site Number : 8400020

    Farmington, Connecticut 06030
    United States

    Active - Recruiting

  • University Of Connecticut Health Center- Site Number : 8400020

    Farmington, Connecticut 06030
    United States

    Active - Recruiting

  • University of Connecticut Health Center- Site Number : 8400020

    Farmington, Connecticut 06032
    United States

    Active - Recruiting

  • Yale New Haven Hospital- Site Number : 8400065

    New Haven, Connecticut 06510
    United States

    Active - Recruiting

  • Advanced Pulmonary Research Institute Site Number : 8400007

    Loxahatchee Groves, Florida 33470
    United States

    Active - Recruiting

  • Advanced Pulmonary Research Institute- Site Number : 8400007

    Loxahatchee Groves, Florida 33470
    United States

    Active - Recruiting

  • Clever Medical Research, LLC Site Number : 8400001

    Miami, Florida 33126
    United States

    Active - Recruiting

  • Clever Medical Research, LLC- Site Number : 8400001

    Miami, Florida 33126
    United States

    Active - Recruiting

  • Clever Medical Research- Site Number : 8400001

    Miami, Florida 33126
    United States

    Active - Recruiting

  • High Quality Research Site Number : 8400047

    Miami, Florida 33184
    United States

    Active - Recruiting

  • High Quality Research- Site Number : 8400047

    Miami, Florida 33184
    United States

    Active - Recruiting

  • My Community Research Center Site Number : 8400023

    Miami, Florida 33155
    United States

    Active - Recruiting

  • My Community Research Center- Site Number : 8400023

    Miami, Florida 33155
    United States

    Active - Recruiting

  • Destiny Research Center- Site Number : 8400049

    Palmetto Bay, Florida 33157
    United States

    Active - Recruiting

  • Avanza Medical Research Center Site Number : 8400018

    Pensacola, Florida 32503
    United States

    Active - Recruiting

  • Avanza Medical Research Center- Site Number : 8400018

    Pensacola, Florida 32503
    United States

    Active - Recruiting

  • Broward Pulmonary and Sleep Specialists Site Number : 8400010

    Plantation, Florida 33324
    United States

    Active - Recruiting

  • Broward Pulmonary and Sleep Specialists- Site Number : 8400010

    Plantation, Florida 33324
    United States

    Active - Recruiting

  • Private Practice - Dr. Frank Hull - Plantation- Site Number : 8400010

    Plantation, Florida 33324
    United States

    Active - Recruiting

  • Northwestern Memorial Hospital- Site Number : 8400043

    Chicago, Illinois 60611
    United States

    Active - Recruiting

  • University of Kansas Medical Center- Site Number : 8400045

    Kansas City, Kansas 66160
    United States

    Active - Recruiting

  • University of Michigan Health System - Ann Arbor- Site Number : 8400055

    Ann Arbor, Michigan 48109
    United States

    Active - Recruiting

  • Pulmonary and Medicine Associates- Site Number : 8400057

    Warren, Michigan 48088
    United States

    Active - Recruiting

  • Washington University- Site Number : 8400046

    Saint Louis, Missouri 63110
    United States

    Active - Recruiting

  • NYU Langone Medical Center- Site Number : 8400032

    New York, New York 10016
    United States

    Active - Recruiting

  • New York University Site Number : 8400032

    New York, New York 10017
    United States

    Active - Recruiting

  • New York University- Site Number : 8400032

    New York, New York 10017
    United States

    Active - Recruiting

  • American Health Research - Charlotte- Site Number : 8400017

    Charlotte, North Carolina 28277
    United States

    Active - Recruiting

  • American Health Research Site Number : 8400017

    Charlotte, North Carolina 28277
    United States

    Active - Recruiting

  • Advanced Respiratory and Sleep Medicine - Huntersville- Site Number : 8400009

    Huntersville, North Carolina 28078
    United States

    Active - Recruiting

  • Advanced Respiratory and Sleep Medicine Site Number : 8400009

    Huntersville, North Carolina 28078
    United States

    Active - Recruiting

  • Southeastern Research Center Site Number : 8400008

    Winston-Salem, North Carolina 27103
    United States

    Active - Recruiting

  • Southeastern Research Center- Site Number : 8400008

    Winston-Salem, North Carolina 27103
    United States

    Active - Recruiting

  • Clinical Research Associates of Central PA - Dubois- Site Number : 8400005

    DuBois, Pennsylvania 15801
    United States

    Active - Recruiting

  • Clinical Research of Central PA Site Number : 8400005

    DuBois, Pennsylvania 15801
    United States

    Active - Recruiting

  • Penn Medicine: University of Pennsylvania Health System- Site Number : 8400039

    Philadelphia, Pennsylvania 19104
    United States

    Active - Recruiting

  • Temple University Hospital Site Number : 8400015

    Philadelphia, Pennsylvania 19140-5103
    United States

    Active - Recruiting

  • Temple University Hospital- Site Number : 8400015

    Philadelphia, Pennsylvania 19140
    United States

    Active - Recruiting

  • Medical University Of South Carolina- Site Number : 8400027

    Charleston, South Carolina 29425
    United States

    Active - Recruiting

  • Medical University of South Carolina - Charleston - Jonathan Lucas Street- Site Number : 8400027

    Charleston, South Carolina 29425
    United States

    Active - Recruiting

  • Metroplex Pulmonary and Sleep Center Site Number : 8400014

    McKinney, Texas 75069
    United States

    Active - Recruiting

  • Metroplex Pulmonary and Sleep Center- Site Number : 8400014

    McKinney, Texas 75069
    United States

    Active - Recruiting

  • Clincove: Plano Primary Care Clinic Site Number : 8400019

    Plano, Texas 75024
    United States

    Active - Recruiting

  • Clincove: Plano Primary Care Clinic- Site Number : 8400019

    Plano, Texas 75024
    United States

    Active - Recruiting

  • Plano Primary Care Clinic- Site Number : 8400019

    Plano, Texas 75024
    United States

    Active - Recruiting

  • Pioneer Research Solutions, Inc. Site Number : 8400048

    Sugar Land, Texas 77479
    United States

    Active - Recruiting

  • Pioneer Research Solutions, Inc.- Site Number : 8400048

    Sugar Land, Texas 77479
    United States

    Active - Recruiting

  • The University of Texas Health Center at Tyler- Site Number : 8400053

    Tyler, Texas 75708
    United States

    Active - Recruiting

  • The University of Texas Health Science Center at Tyler- Site Number : 8400053

    Tyler, Texas 75708
    United States

    Active - Recruiting

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