A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

Last updated: January 9, 2025
Sponsor: Takeda
Overall Status: Active - Recruiting

Phase

3

Condition

Skin Wounds

Rosacea

Psoriasis And Psoriatic Disorders

Treatment

TAK-279

Clinical Study ID

NCT06323356
TAK-279-PsO-3005
jRCT2031230714
  • Ages > 18
  • All Genders

Study Summary

The main aim of this study is to check if TAK-279 improves symptoms of With Generalized Pustular Psoriasis (GPP) or Erythrodermic Psoriasis (EP) and side effect from the study treatment or TAK-279.

All participants will be assigned to study treatments of TAK-279 and will be treated with TAK-279 if the participants meet the study rules.

Participants will be in the study for up to 61 weeks including 52 weeks of study treatment. During the study, participants will visit their study clinic for multiple times.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. A diagnosis of GPP or EP prior to the screening visit.

  2. Candidate for phototherapy or systemic therapy.

Exclusion

Exclusion Criteria:

  1. Other forms of psoriasis.

  2. History of recent infection.

  3. Any prior exposure to TAK-279, or participation in any study that included a TYK2inhibitor.

Other protocol defined inclusion/exclusion criteria apply.

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: TAK-279
Phase: 3
Study Start date:
March 19, 2024
Estimated Completion Date:
March 27, 2026

Connect with a study center

  • Nagoya City University Hospital

    Nagoya, Aichi
    Japan

    Active - Recruiting

  • Fujita Health University Hospital

    Toyoake, Aichi
    Japan

    Active - Recruiting

  • Kimitsu Chuo Hospital

    Kisarazu, Chiba
    Japan

    Active - Recruiting

  • Juntendo University Urayasu Hospital

    Urayasu, Chiba
    Japan

    Active - Recruiting

  • Hospital of the University of Occupational and Environmental Health, Japan

    Kitakyushu, Fukuoka
    Japan

    Active - Recruiting

  • Isesaki Municipal Hospital

    Isesaki, Gunma
    Japan

    Active - Recruiting

  • Kobe University Hospital

    Kobe, Hyogo
    Japan

    Active - Recruiting

  • Tokai University Hospital

    Isehara, Kanagawa
    Japan

    Active - Recruiting

  • Mie University Hospital

    Tsu, Mie
    Japan

    Active - Recruiting

  • Kansai Medical University Hospital

    Hirakata, Osaka
    Japan

    Active - Recruiting

  • Saitama Medical University Hospital

    Iruma, Saitama
    Japan

    Active - Recruiting

  • St.Luke's International Hospital

    Chuo City, Tokyo
    Japan

    Active - Recruiting

  • Teikyo University Hospital

    Itabashi-ku, Tokyo
    Japan

    Active - Recruiting

  • The Jikei University Hospital

    Minato-ku, Tokyo
    Japan

    Active - Recruiting

  • Tokyo Medical University Hospital

    Shinjuku-ku, Tokyo
    Japan

    Active - Recruiting

  • Fukuoka University Hospital

    Fukuoka,
    Japan

    Active - Recruiting

  • University Hospital, Kyoto Prefectural University of Medicine

    Kyoto,
    Japan

    Active - Recruiting

  • Okayama University Hospital

    Okayama,
    Japan

    Active - Recruiting

  • Nippon Life Hospital

    Osaka,
    Japan

    Active - Recruiting

  • Osaka Metropolitan University Hospital

    Osaka,
    Japan

    Active - Recruiting

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