Chronic Post Surgical Pain-Cardiac

Last updated: June 11, 2024
Sponsor: Ondokuz Mayıs University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT06382077
CPSP5502
  • Ages 18-80
  • All Genders

Study Summary

The CPSP-Cardiac is a large, multi-center, observational study with the aim to investigate the incidence of chronic pain in the 3rd month postoperatively in cardiac surgery and its affecting factors.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • patients will be undergoing a first-time cardiac surgery involving a mediansternotomy, including coronary artery bypass grafting (CABG) and all open-heartprocedures, such as valvular repairs/replacement.

  • patients between the ages of 18-80 years

  • American Society of Anesthesiologists (ASA) Physical Status score of II-III

  • patients will also sign the written informed consent form

Exclusion

Exclusion Criteria:

  • patients scheduled for minimally invasive cardiac surgery,

  • patients with BMI>40,

  • patients who undergone thoracotomy,

  • patients with alcohol and drug addiction,

  • patients with severe dysfunction in a significant organ (e.g., presence of severehepatic and renal disease),

  • patients who undergone emergency and redo surgeries,

  • patients who cannot be extubated within the first 8 hours postoperatively,

  • patients have a severe psychiatric diseases such as psychosis or dementia thatrestrict cooperation with the patient (patients who cannot evaluate verbal numericalpain scales),

  • patients who are pregnant and breastfeeding,

  • patients who cannot be reached by phone during the postoperative follow-up periods

  • patients who cannot communicate in the native language.

Study Design

Total Participants: 1176
Study Start date:
May 07, 2024
Estimated Completion Date:
October 25, 2025

Study Description

Cardiovascular diseases pose a significant global health concern, particularly among the elderly population, leading to a surge in surgical interventions. Enhanced Recovery After Surgery (ERAS®) protocols, specifically ERAS® Cardiac, target improved perioperative pain management to optimize patient outcomes. Effective pain control aims to alleviate acute discomfort, prevent chronic pain development, facilitate early mobilization, reduce hospital stays, and enhance patient satisfaction and functional recovery. While pain intensity peaks within the initial days following cardiac surgery and gradually subsides, inadequate acute pain management can predispose patients to chronic pain, impairing their quality of life. Multimodal opioid-sparing analgesia strategies are recommended, with recent advancements in ultrasound-guided regional anesthesia techniques showing promise in enhancing acute pain relief and reducing opioid consumption, particularly through truncal fascial plane blocks and parasternal blocks. However, the impact of these techniques on chronic postsurgical pain remains incompletely understood. This multicenter study aims to investigate the incidence of chronic postsurgical pain following cardiac surgery, exploring the influence of various factors and their implications on patients' quality of life.

Connect with a study center

  • Ondokuz Mayis University

    Samsun, Atakum 55139
    Turkey

    Active - Recruiting

  • Baskent University

    Adana,
    Turkey

    Active - Recruiting

  • Adiyaman Üniversitesi

    Adıyaman,
    Turkey

    Active - Recruiting

  • Ankara University

    Ankara,
    Turkey

    Active - Recruiting

  • Bilkent City Hospital

    Ankara,
    Turkey

    Active - Recruiting

  • Hacettepe Üniversitesi

    Ankara,
    Turkey

    Active - Recruiting

  • Akdeniz University

    Antalya,
    Turkey

    Active - Recruiting

  • Antalya Eah

    Antalya,
    Turkey

    Active - Recruiting

  • Bursa City Hospital

    Bursa,
    Turkey

    Active - Recruiting

  • Bursa Yuksek Ihtisas Eah

    Bursa,
    Turkey

    Active - Recruiting

  • Uludağ Üniversitesi

    Bursa,
    Turkey

    Active - Recruiting

  • Denizli Dh

    Denizli,
    Turkey

    Active - Recruiting

  • Düzce Üniversitesi

    Düzce,
    Turkey

    Active - Recruiting

  • Ataturk University

    Erzurum,
    Turkey

    Active - Recruiting

  • Sanko Üniversitesi

    Gaziantep,
    Turkey

    Active - Recruiting

  • Süleyman Demirel Üniversitesi

    Isparta,
    Turkey

    Active - Recruiting

  • Acibadem Atasehir Hospital

    Istanbul,
    Turkey

    Active - Recruiting

  • Basahsehir Cam and Sakura Hospital

    Istanbul,
    Turkey

    Active - Recruiting

  • Cemil Taşçioğlu Şehir Hastanesi

    Istanbul,
    Turkey

    Active - Recruiting

  • Istanbul University

    Istanbul,
    Turkey

    Active - Recruiting

  • Kartal Kosuyolu Eah

    Istanbul,
    Turkey

    Active - Recruiting

  • Koç University Hospital

    Istanbul,
    Turkey

    Active - Recruiting

  • Marmara University

    Istanbul,
    Turkey

    Active - Recruiting

  • Kocaeli University

    Kocaeli,
    Turkey

    Active - Recruiting

  • Kocaeli Şehir Hastanesi

    Kocaeli,
    Turkey

    Active - Recruiting

  • Mersin University

    Mersin,
    Turkey

    Active - Recruiting

  • Muğla Eah

    Muğla,
    Turkey

    Active - Recruiting

  • Recep Tayyip Erdoğan Üniversitesi

    Rize,
    Turkey

    Active - Recruiting

  • Burhan Dost

    Samsun, 55270
    Turkey

    Site Not Available

  • Samsun University

    Samsun,
    Turkey

    Active - Recruiting

  • Karadeniz Teknik University

    Trabzon,
    Turkey

    Active - Recruiting

  • Trabzon Ahi Avran Eah

    Trabzon,
    Turkey

    Active - Recruiting

  • Canakkale University

    Çanakkale,
    Turkey

    Active - Recruiting

  • Hitit University

    Çorum,
    Turkey

    Active - Recruiting

  • Medipol Mega Hospital

    İ̇stanbul,
    Turkey

    Active - Recruiting

  • Şanliurfa Eah

    Şanlıurfa,
    Turkey

    Active - Recruiting

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