Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Registry)

Inclusion Criteria:

1. Age ≥ 18 years

2. Patient with stable coronary artery disease, non-ST-elevation myocardial infarction,or unstable angina

3. Left main disease confirmed by coronary angiography or coronary CT angiography

4. Clinical and anatomical eligibility for PCI as agreed by the local Heart Team

5. Patient with consent prior to undergoing PCI

6. Left main Medina classification (1,1,1), (1,0,1), (0,1,1), (0,0,1) confirmed bycoronary angiography

7. De novo target lesion in LMT-LAD amenable for crossover stenting with provisionalside-branch approach as determined by PCI operator

8. De novo ostial LCx lesions

9. Lesion indicated in No. 8 with a length of less than 10 mm or a stenosis of lessthan 70% confirmed by coronary angiography

Exclusion Criteria:

1. Inability to provide written informed consent

2. Patient with a history of ST-elevation myocardial infarction within the previous 1week

3. Patient in a state of cardiogenic shock

4. Patient with a history of coronary artery bypass grafting

5. Patient with malignant tumors or other conditions with a life expectancy of lessthan one year

6. Patient considered suitable for stent placement in the ostial LCx from a medicalperspective

7. Patient considered unsuitable for anti-thrombotic therapy after PCI

8. Other patient whom the investigator deems unsuitable for the safe conduct of LM-PCI,including W-KBT