Recession Coverage Using Modified Coronally Advanced Tunnel(MCAT)

Phase

N/A

Condition

Periodontitis

Treatment

MCAT + subepithelial connective tissue graft + enamel matrix derivative

MCAT + subepithelial connective tissue graft

MCAT + enamel matrix derivate

Clinical Study ID

NCT06504329

Mcat-microsurgery

Ages 18-45
All Genders
Accepts Healthy Volunteers

Study Summary

In our study, patients with Miller Class I and II gingival recession will be divided into three groups to undergo the modified coronally advanced tunnel (MCAT) technique using connective tissue grafts, enamel matrix derivatives, or a combination of connective tissue grafts and enamel matrix derivatives. The short- and long-term success of these groups will be evaluated. There are limited studies on the MCAT technique in the literature, and our objectives and anticipated outcomes upon completion of the project are as follows:

Evaluation of the success of the MCAT technique in root coverage.
Evaluation of the aesthetic outcomes of the MCAT technique.
Evaluation of the impact of the MCAT technique on postoperative patient comfort and morbidity.
Assessment of the effect of enamel matrix derivative (Emdogain) application on treatment outcomes.
Assessment of the effect of connective tissue graft on treatment outcomes.
Investigation of the additional benefits of combining connective tissue grafts with enamel matrix derivatives.
Evaluation of the long-term outcomes of gingival recession treatment.

By focusing on these goals, the investigators aim to provide comprehensive insights into the efficacy and benefits of the MCAT technique and its variations in treating gingival recession.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Volunteers aged between 18-45 years.
No previous surgical procedures should have been performed in the selected areas.
Presence of periodontal pockets not exceeding 3 mm in treated teeth; absence ofocclusal trauma.
Not being pregnant or breastfeeding, and not undergoing any regulatory drugtreatment.
Patients presenting with various periodontal problems who have received indicationsfor modified coronally advanced tunnel due to gingival recession in theperiodontology clinic.
Absence of any systemic condition that could interfere with surgical procedures.

Exclusion

Exclusion Criteria:

Exclusion criteria and refusal to participate in the study.

Study Design

MCAT + subepithelial connective tissue graft + enamel matrix derivative

May 24, 2024

November 24, 2024

Study Description

This study is planned to be conducted with 60 individuals, aged between 18 and 45, who have presented to the Department of Periodontology at Necmettin Erbakan University Faculty of Dentistry for various reasons. Routine initial periodontal examinations and Phase 1 periodontal treatments will be performed on individuals exhibiting gingival recession and associated sensitivity. Standard mucogingival surgical procedures are routinely applied in our faculty to these individuals.

In our study, the short- and long-term outcomes of the MCAT technique, a mucogingival approach, will be evaluated. The study will consist of the following three groups:

Group 1: Modified coronally advanced tunnel (MCAT) + subepithelial connective tissue graft (n:20) Group 2: Modified coronally advanced tunnel (MCAT) + enamel matrix derivative(n:20) Group 3: Modified coronally advanced tunnel (MCAT) + subepithelial connective tissue graft + enamel matrix derivative(n:20)

Our study is designed as a randomized, controlled clinical trial. Measurements will include gingival thickness, the amount of root coverage, and keratinized gingiva parameters, recorded using a Williams probe (Hu-Friedy) and rounded to the nearest millimeter.

For gingival recession, plaque index, and gingival index will be obtained from three points: mesial, distal, and midpoints. The plaque index will be calculated according to the criteria defined by Silness and Loe, while the gingival index will be assessed based on the criteria defined by Loe and Silness. Gingival thickness will be measured 3 mm below the gingival margin under topical anesthesia using an endodontic reamer with a stopper.

Patients will be asked to complete a chart rating their subjective pain, burning sensation, and discomfort in the surgical area on a visual analogue scale (VAS) ranging from 0 (none) to 100 (very severe) on postoperative days 3 and 7. The clinician will remove the sutures two weeks after surgery and will complete the wound healing index for each tooth individually according to Huang's criteria.

This study aims to provide comprehensive insights into the effectiveness and benefits of the MCAT technique and its variations in treating gingival recession.

Connect with a study center

Necmettin Erbakan University, Faculty of Dentistry
Konya,
Turkey
Active - Recruiting

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