Observing Physiological Changes in Patients With Long-term Oxygen Therapy

Last updated: July 25, 2024
Sponsor: Insel Gruppe AG, University Hospital Bern
Overall Status: Active - Recruiting

Phase

N/A

Condition

Chronic Bronchitis

Treatment

LTOT

Clinical Study ID

NCT06525857
STD0006706
  • Ages > 18
  • All Genders

Study Summary

In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life.

For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 18-year-old, and

  • Chronic respiratory disease including a) chronic obstructive pulmonary disease, b)interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and

  • Prescribed new LTOT due to a chronic respiratory disease with resting and/orexertional hypoxemia, and

  • Able to speak/read/understand German or French, and

  • Willing and able to understand and provide signed informed consent

Exclusion

Exclusion Criteria:

  • Pregnant or lactating women, or

  • Inability to follow the procedures/instructions of the study (e.g. due to language,psychological disorders, dementia, etc.), or

  • Patients having a subordination link to the investigators, or

  • Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heartdisease, sleep associated breathing disorder, neuromuscular disease or lung cancer,or

  • Known participation in another human research project (ClinO/HRO) that may affectthe objectives of this study.

Study Design

Total Participants: 40
Treatment Group(s): 1
Primary Treatment: LTOT
Phase:
Study Start date:
June 01, 2024
Estimated Completion Date:
January 31, 2026

Connect with a study center

  • Inselspital, Bern University Hospital

    Bern, 3010
    Switzerland

    Active - Recruiting

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