Phase
Condition
Extraction
Treatment
Dexamethasone 4mg/ml solution
Clinical Study ID
Ages 18-89 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Male or female patient aged 18 to 89
One tooth, excluding molars, that has been identified by dental faculty as requiringa single tooth extraction
A dental implant is indicated and treatment planned to replace the missing tooth
Site has adequate restorative space for a dental implant-retained restoration
Site has at least 10mm of alveolar bone height, without impinging on the maxillarysinus or inferior alveolar canal.
Site has a dehiscence of the buccal or lingual bony plate of the tooth socketextending no more than 50% of the total depth of the socket.
Female patients who have undergone a hysterectomy, tubal ligation, or menopause, andnon-pregnant women of child-bearing potential.
Patients are nonsmokers or former smokers. Current smokers may be included if theysmoke <10 cigarettes per day
Exclusion
Exclusion Criteria:
Patient allergic to dexamethasone
Will not cooperate with the follow-up schedule.
Patients will not be entered who are mentally incompetent, prisoners, or pregnant.
Pregnant women or women intending to become pregnant during the study period (asconfirmed verbally; an over-the-counter pregnancy test will be provided if pregnancystatus is unknown or suspected). Patients who become pregnant during the study willbe withdrawn and standard care will be delivered.
Smokers who smoke >10 cigarettes per day
Clinical and/or radiographic determinations which will preclude inclusion in thisstudy are: Active infection other than periodontitis; Inadequate bone dimensions orrestorative space for a dental implant; Presence of a disease entity, condition ortherapeutic regimen which decreases probability of soft tissue and bony healing,e.g., poorly controlled diabetes, chemotherapeutic and immunosuppressive agents,autoimmune diseases, history of bisphosphonate use or long-term steroid therapy.
Study Design
Study Description
Connect with a study center
UT Health Science Center at San Antonio, School of Dentistry
San Antonio, Texas 78229
United StatesActive - Recruiting
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