Eating Disorders Genetics Initiative 2

Last updated: January 21, 2025
Sponsor: University of North Carolina, Chapel Hill
Overall Status: Active - Recruiting

Phase

N/A

Condition

Vomiting

Anorexia

Bulimia

Treatment

Eating disorder diagnosis group

Clinical Study ID

NCT06594913
23-2887
R01MH136156
R01MH136149
R01MH136157
  • Ages 12-99
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder,avoidant restrictive food intake disorders or no history of any disordered eatingbehavior, based on DSM-5 criteria algorithms

  • Age 12-99 years, depending on country. (US enrollment age is 18-99)

Exclusion

Exclusion Criteria:

  • History of subthreshold disordered eating behaviors.

Study Design

Total Participants: 20000
Treatment Group(s): 1
Primary Treatment: Eating disorder diagnosis group
Phase:
Study Start date:
October 28, 2024
Estimated Completion Date:
August 01, 2027

Connect with a study center

  • QIMR Berghofer

    Brisbane, Queensland
    Australia

    Active - Recruiting

  • Comenzar de Nuevo

    Monterrey,
    Mexico

    Site Not Available

  • University of Otago

    Christchurch, Canterbury
    New Zealand

    Active - Recruiting

  • Karolinska Institutet

    Stockholm,
    Sweden

    Active - Recruiting

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina 27599-7160
    United States

    Active - Recruiting

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