Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

Last updated: February 20, 2026
Sponsor: University of California, San Francisco
Overall Status: Active - Recruiting

Phase

N/A

Condition

Aging

Treatment

MediTrain

Sleep monitor

wrist worn multi-sensor watches

Clinical Study ID

NCT06633978
AG083503
R61AG083503
  • Ages 60-85
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The goal of this proposed research is to collect pilot data to test the hypothesis that treatment with a novel form of closed-loop digital meditation (MediTrain) will lead to a greater magnitude of gains in cognitive abilities in patients with mild cognitive impairment (MCI), compared to OA without cognitive impairment, and will lead to improvements in quantitative measures of sleep.

Eligibility Criteria

Inclusion

  • comfortably ambulatory healthy physical condition

  • normal or corrected to normal visual

  • auditory acuity

  • fluency in spoken English

  • Between 60-85 years old

  • No neurological or psychiatric disorders

  • No substance abuse

  • Not taking anti-depressants

  • Not taking anti-anxiety medication

  • No history of seizures

  • No color blindness

  • No glaucoma

  • No macular degeneration

  • No amblyopia (lazy eye)

  • No strabismus (cross eyed)

  • Aneurysm clip(s)

  • No Cardiac pacemaker

  • No Implanted cardioverter defibrillator (ICD)

  • No Electronic implant or device

  • No Magnetically-activated implant or device

  • No Neurostimulation system

  • No Spinal cord stimulator

  • No Internal electrodes or wires

  • No Bone growth/bone fusion stimulator

  • No Cochlear, otologic, or other ear implant

  • No Insulin or other infusion pump

  • No Implanted drug infusion device

  • No type of prosthesis (eye, penile, etc.)

  • No Heart valve prosthesis

  • No Eyelid spring or wire

  • No Artificial or prosthetic limb

  • No Metallic stent, filter, or coil

  • No Shunt (spinal or intraventricular)

  • No Vascular access port and/or catheter

  • No Radiation seeds or implants

  • No Swan-Ganz or thermodilution catheter

  • No Medication patch (Nicotine, Nitroglycerine)

  • No metallic fragment or metallic foreign body in/on the body that can not be removed

  • No Wire mesh implant

  • No Tissue expander (e.g., breast)

  • No Surgical staples, clips, or metallic sutures

  • No Joint replacement (hip, knee, etc.)

  • No Bone/joint pin, screw, nail, wire, plate, etc.

  • No IUD, diaphragm, or pessary

  • No Dentures or partial plates that can not be removed

  • No Tattoo or permanent makeup

  • No Body piercing jewelry

  • No Claustrophobia

Study Design

Total Participants: 90
Treatment Group(s): 3
Primary Treatment: MediTrain
Phase:
Study Start date:
September 10, 2024
Estimated Completion Date:
August 31, 2026

Connect with a study center

  • University of California, San Francisco

    San Francisco, California 94158
    United States

    Site Not Available

  • University of California, San Francisco

    San Francisco 5391959, California 5332921 94158
    United States

    Active - Recruiting

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