Phase
Condition
Carcinoma
Solid Tumors
Treatment
CBA-1205
Clinical Study ID
Ages > 20 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Patients who provide voluntary written informed consent to participate in the study
Patients with an Eastern Cooperative Oncology Group (ECOG) performance status (PS)of≤1
Patients with preserved renal function as evidenced by laboratory data obtainedwithin 7 days before enrollment (creatinine: ≤ ULN ×1.5)
Patients who meet the following laboratory criteria of bone marrow function asevidenced by laboratory data obtained within 7 days before enrollment:
Neutrophil count;≥1500/μL, Platelet count; ≥75000/μL, Hemoglobin;≥9.0 g/dL.
Patients having solid tumors with no standard therapy available or refractory orintolerable to standard therapy
Patients with unresectable advanced/recurrent hepatocellular carcinoma refractory orintolerable to standard therapy (Part2, 3: HCC)
Patients with Child-Pugh A or B (Part2, 3; HCC)
Exclusion
Exclusion criteria:
Patients who have undergone major surgery within 28 days before enrollment
Patients who have received anticancer treatment with surgical therapy, radiationtherapy, and/or drug therapy within 14 days before enrollment
Patients who have received anticancer treatment with immune checkpoint inhibitor,etc. within 28 days before enrollment
Patients with Grade 2 or higher concurrent disease or prior therapy-related toxicity
Patients who have received any other investigational product within 28 days beforeenrollment
Patients with current or previous inadequately controlled or clinically significantcardiac disease
Patients who, in the opinion of the investigator or subinvestigator, is notappropriate
Study Design
Study Description
Connect with a study center
National Cancer Center Hospital East
Kashiwa, Chiba
JapanActive - Recruiting
Kanagawa Cancer Center
Yokohama, Kanagawa
JapanActive - Recruiting
National Cancer Center Hospital
Chuo, Tokyo
JapanActive - Recruiting
Niigata University Medical and Dental Hospital
Niigata,
JapanActive - Recruiting
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