Predict Tooth Wear

Last updated: November 7, 2024
Sponsor: Hospices Civils de Lyon
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Tooth Shape assessed using an intraoral scanner one after avulsion

Clinical Study ID

NCT06681844
69HCL23_1046
  • Ages 18-80
  • All Genders

Study Summary

Tooth wear, resulting from gradual loss of dental hard tissue due to mechanical and chemical factors, impacts tooth structure, texture, and function. It affects quality of life, with varying prevalence (26.9% to 90.0%), and is traditionally detected visually during check-ups, often at advanced stages. Monitoring alterations in tooth shape via intraoral scanners aids early detection, but restoration remains challenging. Prevention through early detection is vital, as patients may not fully comprehend tooth structure loss until visible. Recently, statistical shape analysis (SSA) used to learn the tooth anatomy and define a reference shape (biogeneric tooth) using. However, assuring landmark consistency is challenging mostly due to biases of the operator. Recently, a robust method called MEG-IsoQuad offered automated, isotopological remeshing. Combining this with SSA holds promise for diagnostic and simulation purposes. This study aims to assess the reliability of a remeshing-SSA approach for altered and intact premolar analysis and compare machine learning algorithms for simulating the shape of the initially intact tooth or future altered one.

The clinical perspective of the current work offers possibilities to:

  • Prevent future tooth wear by detecting it at an early stage; and communicate better to the patient by presenting him/her potential future altered teeth

  • Simulate the adapted reconstruction for the altered tooth by simulating the initially intact one

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • teeth avulsed presenting a tooth wear index between 0 and 3

  • mature incisor, canine, premolar or molars (1st and 2nd only)

Exclusion

Exclusion Criteria:

  • teeth avulsed presenting a tooth wear index over 3 (or presenting an oralrehabilitation representative of a similar wear)

  • immature teeth or teeth without root edification

  • wisdom teeth

Study Design

Total Participants: 1000
Treatment Group(s): 1
Primary Treatment: Tooth Shape assessed using an intraoral scanner one after avulsion
Phase:
Study Start date:
December 12, 2023
Estimated Completion Date:
December 31, 2027

Connect with a study center

  • KU Leuven University Hospital

    Leuven,
    Belgium

    Active - Recruiting

  • Lyon Dental Hospital

    Lyon, 69007
    France

    Active - Recruiting

  • King George Medical University

    Lucknow,
    India

    Active - Recruiting

  • Tel Aviv Universi

    Tel Aviv,
    Israel

    Active - Recruiting

  • Indiana University Hospital

    Indianapolis, Indiana 46202
    United States

    Active - Recruiting

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