Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Attacks In Canada

Last updated: February 28, 2025
Sponsor: AbbVie
Overall Status: Active - Recruiting

Phase

N/A

Condition

Headaches

Chronic Pain

Pain (Pediatric)

Treatment

N/A

Clinical Study ID

NCT06692881
P25-245
  • Ages > 18
  • All Genders

Study Summary

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate function and satisfaction with oral ubrogepant in treating adult participants after multiple migraine attacks.

Ubrogepant is a drug approved for the acute treatment of migraine in adults. Approximately 167 participants will be enrolled in approximately 10-15 sites across Canada.

Participants will receive ubrogepant as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 12 weeks.

There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participants able to give voluntary informed consent before starting anystudy-related assessments or procedures (to be obtained/documented as per localregulations).

  • Adults (≥18 years of age) at time of informed consent.

  • Participants with at least 1-year history of migraine with or without auraconsistent with a diagnosis according to the ICHD-3 (2018).

  • Participants with history of experiencing at least 3 migraine attacks per month withmoderate to severe symptoms

  • Participants prescribed ubrogepant by investigator for the acute treatment ofmigraine according to local product label, independent of and prior to studyparticipation

  • Participants willing and able to comply with the requirements of the study.

  • Participants with access to an electronic device (mobile phone, tablet, laptop,etc.) with internet access.

Exclusion

Exclusion Criteria:

  • Participants previously exposed to a ubrogepant or rimegepant as routine therapy orthrough a clinical trial.

  • Participants with history of known contraindications to ubrogepant as per locallabeling.

  • Participants Pregnant or planning to be pregnant or of childbearing potential notusing contraception

  • Participants enrolled in any interventional studies that may include investigationalcompounds for migraine or non-AbbVie observational studies.

  • History or current evidence of any condition that might interfere with their abilityto comply with the study requirements, in the opinion of the investigator.

Study Design

Total Participants: 167
Study Start date:
February 12, 2025
Estimated Completion Date:
January 31, 2026

Connect with a study center

  • Dr May Ong INC /ID# 271474

    Vancouver, British Columbia V6Z 2E8
    Canada

    Active - Recruiting

  • Maritime Neurology /ID# 271867

    Halifax, Nova Scotia B3R 1V9
    Canada

    Active - Recruiting

  • Neurocentre of Eastern Ontario /ID# 271865

    Kingston, Ontario K7M 8H9
    Canada

    Active - Recruiting

  • Centricity /ID# 271477

    London, Ontario N6A 2C2
    Canada

    Active - Recruiting

  • 360 Concussion Care /ID# 271972

    Ottawa, Ontario K1H 7X7
    Canada

    Active - Recruiting

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