A Study of ONO-1110 in Patients With Postherpetic Neuralgia

Last updated: February 27, 2026
Sponsor: Ono Pharmaceutical Co. Ltd
Overall Status: Active - Not Recruiting

Phase

2

Condition

Pain (Pediatric)

Pain

Postherpetic Neuralgia

Treatment

ONO-1110

Placebo

Clinical Study ID

NCT06708416
ONO-1110-04
jRCT2031240504
  • Ages > 18
  • All Genders

Study Summary

To evaluate the efficacy and safety of ONO-1110 in Japanese patients with postherpetic neuralgia

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Japanese (both sexes)

  • Age (at the time of informed consent): 18 years and older

  • Outpatient

  • Patients with persistent pain ≥3 months (90 days) after the onset of herpes zoster

  • Patients who are considered capable of understanding the study procedures andcompleting the pain diary and questionnaires appropriately by the investigator (sub-investigator)

Exclusion

Exclusion Criteria:

  • Patients who previously underwent neurodestruction or neurosurgical therapy for PHN

  • Patients with pain other than PHN that may affect assessments in this study

  • Patients with any skin condition related to the site of herpes zoster that mayaffect assessments in this study

  • Patients with a past history of or concurrent neurologic diseases that may affectassessments in this study

  • Patients with concurrent psychiatric diseases that may affect assessments in thisstudy

Study Design

Total Participants: 140
Treatment Group(s): 2
Primary Treatment: ONO-1110
Phase: 2
Study Start date:
February 12, 2025
Estimated Completion Date:
August 31, 2026

Connect with a study center

  • Kamezawa Clinic

    Aichi,
    Japan

    Active - Recruiting

  • Kimura Clinic

    Aichi,
    Japan

    Site Not Available

  • Kamezawa Clinic

    Aichi 11192139,
    Japan

    Site Not Available

  • Kimura Clinic

    Aichi 11192139,
    Japan

    Site Not Available

  • Fukuoka Tokushukai Hospital

    Fukuoka,
    Japan

    Site Not Available

  • Fukuoka Tokushukai Hospital

    Fukuoka 1863967,
    Japan

    Site Not Available

  • Southern Tohoku General Hospital

    Fukushima,
    Japan

    Site Not Available

  • Southern Tohoku General Hospital

    Fukushima 2112923,
    Japan

    Site Not Available

  • Central Japan International Medical Center

    Gifu,
    Japan

    Site Not Available

  • Central Japan International Medical Center

    Gifu 1863641,
    Japan

    Site Not Available

  • National Hospital Organization Kure Medical Center

    Hiroshima,
    Japan

    Site Not Available

  • National Hospital Organization Kure Medical Center

    Hiroshima 1862415,
    Japan

    Site Not Available

  • National Hospital Organization Hokkaido Medical Center

    Hokkaido,
    Japan

    Site Not Available

  • Nishinomiya Municipal Central Hospital

    Hyōgo,
    Japan

    Site Not Available

  • Nishinomiya Municipal Central Hospital

    Hyōgo 2129969,
    Japan

    Site Not Available

  • Mito Saiseikai General Hospital

    Ibaraki,
    Japan

    Site Not Available

  • Mito Saiseikai General Hospital

    Ibaraki 1862033,
    Japan

    Site Not Available

  • Kawasaki Municipal Hospital

    Kanagawa,
    Japan

    Site Not Available

  • Konan Hidamari Pain Clinic

    Kanagawa,
    Japan

    Active - Recruiting

  • Tai Clinic

    Kanagawa,
    Japan

    Active - Recruiting

  • Yokohama City Minato Red Cross Hospital

    Kanagawa,
    Japan

    Active - Recruiting

  • Kawasaki Municipal Hospital

    Kanagawa 1860292,
    Japan

    Site Not Available

  • Konan Hidamari Pain Clinic

    Kanagawa 1860292,
    Japan

    Site Not Available

  • Nomura Dermatology Clinic

    Kanagawa 1860292,
    Japan

    Site Not Available

  • Tai Clinic

    Kanagawa 1860292,
    Japan

    Site Not Available

  • Yokohama City Minato Red Cross Hospital

    Kanagawa 1860292,
    Japan

    Site Not Available

  • Junwakai Memorial Hospital

    Miyazaki,
    Japan

    Site Not Available

  • Medical Corporation Toyama Dermatology

    Miyazaki,
    Japan

    Active - Recruiting

  • Junwakai Memorial Hospital

    Miyazaki 1856717,
    Japan

    Site Not Available

  • Medical Corporation Toyama Dermatology

    Miyazaki 1856717,
    Japan

    Site Not Available

  • Yuaikai Tomishiro Chuo Hospital

    Okinawa,
    Japan

    Site Not Available

  • Yuaikai Tomishiro Chuo Hospital

    Okinawa 1894616,
    Japan

    Site Not Available

  • Morimoto Clinic

    Osaka,
    Japan

    Site Not Available

  • Osaka Metropolitan University Hospital

    Osaka,
    Japan

    Active - Recruiting

  • Morimoto Clinic

    Osaka 1853909,
    Japan

    Site Not Available

  • Osaka Medical and Pharmaceutical University Hospital

    Osaka 1853909,
    Japan

    Site Not Available

  • Osaka Metropolitan University Hospital

    Osaka 1853909,
    Japan

    Site Not Available

  • Shizuoka Rehabili Pain Clinic

    Shizuoka,
    Japan

    Site Not Available

  • Chutoen General Medical Center

    Shizuoka 1851717,
    Japan

    Site Not Available

  • Shizuoka Rehabili Pain Clinic

    Shizuoka 1851717,
    Japan

    Site Not Available

  • Fukuuchi Pain Clinic

    Tokyo,
    Japan

    Active - Recruiting

  • Fukuwa Clinic

    Tokyo,
    Japan

    Active - Recruiting

  • Futaki Skin Care Clinic

    Tokyo,
    Japan

    Active - Recruiting

  • Juntendo University Hospital

    Tokyo,
    Japan

    Active - Recruiting

  • Mitaka Pain Clinic

    Tokyo,
    Japan

    Site Not Available

  • Nishiogi Pain Clinic

    Tokyo,
    Japan

    Active - Recruiting

  • Tokyo-Eki Center-Building Clinic

    Tokyo,
    Japan

    Active - Recruiting

  • Fukuuchi Pain Clinic

    Tokyo 1850147,
    Japan

    Site Not Available

  • Fukuwa Clinic

    Tokyo 1850147,
    Japan

    Site Not Available

  • Futaki Skin Care Clinic

    Tokyo 1850147,
    Japan

    Site Not Available

  • Juntendo University Hospital

    Tokyo 1850147,
    Japan

    Site Not Available

  • Mitaka Pain Clinic

    Tokyo 1850147,
    Japan

    Site Not Available

  • Nishiogi Pain Clinic

    Tokyo 1850147,
    Japan

    Site Not Available

  • Tokyo-Eki Center-Building Clinic

    Tokyo 1850147,
    Japan

    Site Not Available

  • Yamanashi Prefectural Central Hospital

    Yamanashi,
    Japan

    Site Not Available

  • Yamanashi Prefectural Central Hospital

    Yamanashi 11611479,
    Japan

    Site Not Available

  • Medical Corporation Fujigaki Clinic

    Ōita,
    Japan

    Site Not Available

  • Medical Corporation Fujigaki Clinic

    Ōita 1854487,
    Japan

    Site Not Available

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