Phase
Condition
Cervical Cancer
Uterine Disorders
Treatment
Laparoscopic radical hysterectomy incorporating modified tumor-free techniques
Abdominal radical hysterectomy
Clinical Study ID
Ages 18-65 Female
Study Summary
Eligibility Criteria
Inclusion
- Inclusion Criteria:
1.1 Females aged 18 to 65 years old. 1.2 Histologically confirmed primary cervicalsquamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma.
1.3 FIGO 2018 stage IB2. 1.4 The maximum diameter of the cervical lesion measured byMRI is >2 cm and ≤4 cm. For those with MRI contraindications, PET/CT, CT, orultrasound can be used as alternatives.
1.5 Scheduled to receive type C (Q - M classification) radical hysterectomy. 1.6Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1.
1.7 Willing to participate in this trial and sign the informed consent form. 1.8Able to cooperate and complete follow - up and relevant examinations. 1.9 For pre -menopausal women, a negative pregnancy test within 30 days before surgery.
1.10 Laboratory test indicators of vital organs meet the standards
Exclusion
- Exclusion Criteria:
2.1 Special pathological types (gastric - type adenocarcinoma, neuroendocrine carcinoma, clear cell carcinoma, carcinosarcoma, etc.).
2.2 Imaging examinations suggest pelvic or para - aortic lymph node metastasis (MRI or CT shows a short - axis diameter of ≥1.5 cm, or SUV ≥2.5), or histopathology indicates lymph node metastasis.
2.3 History of pelvic and abdominal radiotherapy. 2.4 History of neoadjuvant chemotherapy. 2.5 Uterus larger than that at 10 weeks of pregnancy. 2.6 Contraindications for surgery and anesthesia (such as severe medical comorbidities).
2.7 Patients who cannot tolerate the Trendelenburg position. 2.8 Patients who cannot cooperate with treatment and follow - up. 2.9 Pregnant patients. 2.10 History of other malignancies, except for those who have been cancer - free for more than 3 years with no current evidence of tumor recurrence.
Study Design
Study Description
Connect with a study center
The First Hospital of Lanzhou University
Lanzhou, Gansu 730000
ChinaSite Not Available
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong 510120
ChinaSite Not Available
Cangzhou Central Hospital
Cangzhou, Hebei 061000
ChinaSite Not Available
The Fourth Hospital of Hebei Medical University
Shijiazhuang, Hebei 050011
ChinaSite Not Available
Hunan Provincial Maternal and Child Health Care Hospital
Changsha, Hunan 410000
ChinaSite Not Available
The Second Hospital of Jilin University
Changchun, Jilin 130041
ChinaSite Not Available
Renji Hospital Affiliated to The Shanghai Jiao Tong University Medical School
Shanghai, Shanghai 200001
ChinaSite Not Available
The Fourth Military Medical University, Xijing Hospital
Xi'an, Shanxi 710032
ChinaSite Not Available
Affiliated Hospital of Shanxi University of Traditional Chinese Medicine
Xianyang, Shanxi 712000
ChinaSite Not Available
Affiliated Hospital of North Sichuan Medical College
Nanchong, Sichuan 637000
ChinaSite Not Available
Zhejiang cancer hospital
Hangzhou, Zhejiang 310022
ChinaSite Not Available
Peking Union Medical College Hospital
Beijing, 100079
ChinaActive - Recruiting
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