Strength-Endurance Circuit Training in Parkinson's Disease

Last updated: April 7, 2025
Sponsor: General University Hospital, Prague
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Strength-Endurance Training

Endurance Training

Clinical Study ID

NCT06893055
56125
  • Ages 18-75
  • All Genders

Study Summary

The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.

  • Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training?

Participants will:

  • undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement,

  • visit the clinic twice a week for 1-hour training sessions.

  • selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • age ≥18 years

  • diagnosis of idiopathic Parkinson´s disease

  • Hoehn-Yahr Scale ≤ 2,5

  • stable dopaminergic medication

Exclusion

Exclusion Criteria:

  • age ≥75 years

  • Hoehn-Yahr Scale ≥ 2,5

  • deep brain stimulation

  • presence of freezing

  • Camptocormia

  • inability to walk without support

  • inability to perform study procedures

  • limiting co-morbidities

  • attendance at training sessions below 70%

Study Design

Total Participants: 90
Treatment Group(s): 2
Primary Treatment: Strength-Endurance Training
Phase:
Study Start date:
March 03, 2025
Estimated Completion Date:
March 31, 2027

Connect with a study center

  • Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague

    Prague, 12000
    Czech Republic

    Active - Recruiting

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