Stimulating the Cochlear Apex Without Longer Electrodes

Last updated: March 24, 2025
Sponsor: NYU Langone Health
Overall Status: Active - Recruiting

Phase

N/A

Condition

Deafness

Treatment

Modified surgical approach

Cochlear Nucleus CI632 cochlear implant

Clinical Study ID

NCT06901674
20-01964
5R21DC019743-02
  • Ages 18-90
  • All Genders

Study Summary

The most common cochlear implant intervention provides an electrode array that stimulates less than half of the length of the cochlea, leaving the regions which represent lower frequencies in the normally functioning ear unstimulated. Providing stimulation over the entire cochlea has the potential to improve speech understanding, sound quality, as well as spectral and temporal representation. Increasing the length of the electrode array to cover a greater portion of the cochlea has many potential issues, including increased damage to the cochlea and probability of incomplete insertions. In this study, a new technique is being investigated that allows stimulation across the entire cochlear extent without increasing the length of the electrode array. The purpose of this study is to evaluate the benefit of the new technique on speech understanding outcomes. Additionally, the study will investigate the new configuration to explore how the auditory system encodes temporal and spectral information.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participants in this study must have already been evaluated at the NYU cochlearimplant center as being eligible for a cochlear implant.

  • They must have decided to receive a cochlear implant manufactured by CochlearLimited and have been diagnosed with a moderate to profound sensorineural hearingloss in the ear to be implanted.

  • Individuals who have already been implanted with a cochlear implant manufactured byCochlear Limited with or without this new approach may also participate in thisstudy.

Exclusion

Exclusion Criteria:

  • They are under the age of 18

  • They have not been diagnosed with a moderate to profound sensorineural hearing lossin the ear to be implanted

  • Have >15 years of profound deafness

  • Have not chosen to receive a cochlear implant manufactured by Cochlear Limited

  • Are pregnant or plan to conceive within 6 months of consenting

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: Modified surgical approach
Phase:
Study Start date:
August 01, 2022
Estimated Completion Date:
January 01, 2026

Connect with a study center

  • NYU Langone Health

    New York, New York 10016
    United States

    Active - Recruiting

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