Pneumococcal Infection

Last updated: April 18, 2022
Sponsor: Merck Sharp & Dohme Corp.
Overall Status: Active - Recruiting

Phase

3

Condition

Pneumonia

Treatment

N/A

Clinical Study ID

TX290674
V 110-91
  • Ages 50-100
  • All Genders

Study Summary

The purpose of this study is to evaluate the concomitant and non-concomitant use of messenger ribonucleic acid (mRNA) mRNA-1273, the nucleoside-modified mRNA vaccine for active immunization to prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), with a 23-valent pneumococcal polysaccharide vaccine for the prevention of pneumococcal disease (V110) and, a 15-valent pneumococcal conjugate vaccine (PCV) indicated for the prevention of invasive pneumococcal disease (V114).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 50+
  • Is in good health. Any underlying chronic illness must be documented to be in stable condition.
  • Has received a 2-dose regimen of the Moderna mRNA SARS-CoV-2 vaccine ≥6 months before enrollment.

Exclusion

Exclusion Criteria:

  • Has a current or known history of SARS-CoV-2 infection.
  • Has a history of myocarditis and/or pericarditis.
  • Has a known or suspected impairment of immunological function including, but not limited to, a history of congenital or acquired immunodeficiency, documented human immunodeficiency virus (HIV) infection, functional or anatomic asplenia, or history of autoimmune disease.
  • Has a coagulation disorder contraindicating intramuscular vaccinations.

Study Design

Study Start date:
January 14, 2022
Estimated Completion Date:

Study Description

  • Condition: Pneumococcal Infection
  • Clinical Trial Identifier: NCT05158140
  • Sponsor: Merck Sharp & Dohme Corp.

Looking for participants within a 30 mile radius of the study site.

Connect with a study center

  • Clinical Research of South Florida

    Coral Gables, Florida 33134
    United States

    Active - Recruiting

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