Wolman Disease is a rare genetic disorder that affects the breakdown and metabolism of fats in the body. It is caused by a deficiency of the enzyme lysosomal acid lipase, which results in the accumulation of fats in the liver, spleen, and other organs. Symptoms of Wolman Disease include abdominal distension, vomiting, diarrhea, and failure to thrive, and the condition is usually fatal within the first year of life.