Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease

Last updated: July 26, 2018
Sponsor: Recep Tayyip Erdogan University Training and Research Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Preeclampsia

Periodontitis

Pregnancy Complications

Treatment

N/A

Clinical Study ID

NCT03603236
40465587-28
  • Ages 21-34
  • Female
  • Accepts Healthy Volunteers

Study Summary

The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preeclampsia.

The secondary objective of the study is to analyze the relationship between preeclampsia and periodontal infection, using clinical, biochemical and microbiological methods.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • pregnant women with preeclampsia

    1. weeks of pregnant women with no history of preterm labor

Exclusion

Exclusion Criteria:

  • Genitourinary infection,

  • pregnancy or pre-pregnancy hypertension,

  • HIV infection,

  • diabetes mellitus,

  • multiple pregnancy, preterm labor / low birth weight,

  • smoker and alcohol use history,

  • IVF pregnancy,

  • placental, cervical and uterine anomalies,

  • pregnancy with intrauterine growth retardation,

  • pregnancies with congenital or chromosomal fetal anomalies,

  • significant vaginal bleeding,

  • infertility stories,

  • drug addicts,

  • poor socioeconomic level

Study Design

Total Participants: 100
Study Start date:
February 17, 2018
Estimated Completion Date:
December 15, 2018

Study Description

Preeclampsia is identified as an important cause for mother and newborn mortality. Inspite of extensive research, the exact etiological relations have not been established.

Periodontal disease is a subclinical and persistent infection source which induces the systemic inflammatory reactions and increases the risk of preeclampsia. It is believed that the results will set light to the etiology of preeclampsia and will help to develop strategies to prevent the disease.

Connect with a study center

  • Recep Tayyip Erdogan University Dentistry Faculty

    Rize, 53000
    Turkey

    Site Not Available

  • Recep Tayyip Erdogan University Faculty of Medicine

    Rize, 53000
    Turkey

    Site Not Available

  • Ege University Dentistry Faculty

    İzmir,
    Turkey

    Active - Recruiting

  • İzmir Health Sciences University, Tepecik Training and Research Hospital Department of Obstetrics and Gynecology

    İzmir,
    Turkey

    Active - Recruiting

  • Glaskow Dental School , School of Medicine University of Glasgow

    Glaskow,
    United Kingdom

    Site Not Available

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