AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention

Last updated: January 21, 2026
Sponsor: Brigham and Women's Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Coronary Artery Disease

Hypercholesterolemia

Cardiovascular Disease

Treatment

Electronic health record-based notification of Nanox.AI Coronary Artery Calcification Assessment

Clinical Study ID

NCT06235112
2023P002954
  • Ages 40-75
  • All Genders

Study Summary

AI INFORM is a multicenter randomized trial that will test the hypothesis that providing clinicians information on the presence and amount of coronary artery calcifications (CAC), will result in initiation or intensification of preventive therapies. The study will use a cloud-based artificial intelligence (AI) platform (Nanox.AI) that can analyze non contrast chest CT and estimate the amount of CAC.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients aged between 40-75 with prior chest CT within last 3 years

Exclusion

Exclusion Criteria:

  • Prior coronary artery disease

  • Prior cancer

  • Other life-limiting condition

Study Design

Total Participants: 1500
Treatment Group(s): 1
Primary Treatment: Electronic health record-based notification of Nanox.AI Coronary Artery Calcification Assessment
Phase:
Study Start date:
July 31, 2024
Estimated Completion Date:
December 01, 2027

Connect with a study center

  • Brigham and Women's Hospital

    Boston, Massachusetts 02445
    United States

    Site Not Available

  • Brigham and Women's Hospital

    Boston 4930956, Massachusetts 6254926 02445
    United States

    Active - Recruiting

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