Respiratory Rehabilitation and Sleep Quality in COPD Patients

Inclusion Criteria:

• Male or female ≥ age 50

• COPD defined according to the GOLD 2022 criteria, clinically stable (withoutexacerbation for at least 4 weeks), with indication for respiratory rehabilitation

• Absence of respiratory rehabilitation in the past 12 months

• Patient affiliated to the social security system

• For women of childbearing potential who have been on effective contraception (estrogen-progestogen or intrauterine device or tubal ligation) for 1 month.

• For postmenopausal women: confirmatory diagnosis (non-medically induced amenorrheafor at least 12 months prior to the inclusion visit)

• Patient who has read and understood the information letter and signed the consentform

Exclusion Criteria:

• BMI≥ 30 kg/m2

• Previously documented OSA (AHI > 10/h)

• Patient with a CPAP or NIV

• Patient on systemic corticosteroid therapy

• Patient on centrally acting therapy (benzodiazepine or opiate)

• Patient with an occurrence of severe COPD exacerbation

• Patient with other associated chronic respiratory insufficiency

• Patient with active cancer

• Patient with neuromuscular disease

• Patient with an osteoarticular disability or traumatic or neurological sequelaepreventing participation in the respiratory rehabilitation program

• Psychiatric, cognitive or linguistic disorders with inability to understand tofollow the protocol

• Patient with a contraindication to respiratory rehabilitation or any pathologypreventing physical rehabilitation

• Patient with a cardiovascular contraindication to respiratory rehabilitation

• Person deprived of liberty by an administrative or judicial decision or personplaced under judicial safeguard, guardianship or curatorship

• Person subject to a legal protection measure

• Pregnant or parturient or breastfeeding woman